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Kura Oncology, Inc. (NASDAQ:KURA) announced Friday that it has received a $30 million milestone payment from Kyowa Kirin, Inc. and Kyowa Kirin Co., Ltd. The payment follows the dosing of the first patient in the KOMET-017 Phase 3 registrational trials of ziftomenib, an investigational oral menin inhibitor. The company, currently valued at approximately $790 million, maintains a strong financial position with more cash than debt and a healthy current ratio of 6.16x.
The KOMET-017 trials, launched on September 29, are global, randomized, double-blind, placebo-controlled Phase 3 studies. They are designed to evaluate ziftomenib in combination with both intensive and non-intensive chemotherapy regimens for patients with newly diagnosed NPM1-mutated or KMT2A-rearranged acute myeloid leukemia.
The milestone payment is part of a collaboration and license agreement between Kura Oncology and Kyowa Kirin. According to the company, the KOMET-017 program consists of two independent trials and is being conducted to assess the safety and efficacy of ziftomenib in these patient populations.
This information is based on a statement included in a Securities and Exchange Commission filing by Kura Oncology.
In other recent news, Kura Oncology announced it received a $30 million milestone payment from Kyowa Kirin. This payment was triggered by the dosing of the first patient in its Phase 3 clinical program for ziftomenib, advancing the treatment into late-stage development for acute myeloid leukemia. Additionally, Kura Oncology presented promising data at the European Society for Medical Oncology Congress, showcasing the potential of its drug darlifarnib as a combination therapy. The clinical data indicated that darlifarnib, when combined with the multi-kinase inhibitor cabozantinib, showed objective response rates of 33%-50% in renal cell carcinoma patients. Analyst firm H.C. Wainwright reiterated a Buy rating with a $40 price target, emphasizing the enhanced antitumor activity of Kura’s farnesyl transferase inhibitor candidates in solid tumor patients. Citizens also maintained a Market Outperform rating with a $24 price target, highlighting the significance of Kura’s recent clinical presentations. These developments underscore the ongoing progress and interest in Kura Oncology’s research and potential treatments.
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