Kura Oncology receives $30 million milestone payment for Phase 3 trial progress

Published 24/10/2025, 12:34
Kura Oncology receives $30 million milestone payment for Phase 3 trial progress

Kura Oncology, Inc. (NASDAQ:KURA) announced Friday that it has received a $30 million milestone payment from Kyowa Kirin, Inc. and Kyowa Kirin Co., Ltd. The payment follows the dosing of the first patient in the KOMET-017 Phase 3 registrational trials of ziftomenib, an investigational oral menin inhibitor. The company, currently valued at approximately $790 million, maintains a strong financial position with more cash than debt and a healthy current ratio of 6.16x.

The KOMET-017 trials, launched on September 29, are global, randomized, double-blind, placebo-controlled Phase 3 studies. They are designed to evaluate ziftomenib in combination with both intensive and non-intensive chemotherapy regimens for patients with newly diagnosed NPM1-mutated or KMT2A-rearranged acute myeloid leukemia.

The milestone payment is part of a collaboration and license agreement between Kura Oncology and Kyowa Kirin. According to the company, the KOMET-017 program consists of two independent trials and is being conducted to assess the safety and efficacy of ziftomenib in these patient populations.

This information is based on a statement included in a Securities and Exchange Commission filing by Kura Oncology.

In other recent news, Kura Oncology announced it received a $30 million milestone payment from Kyowa Kirin. This payment was triggered by the dosing of the first patient in its Phase 3 clinical program for ziftomenib, advancing the treatment into late-stage development for acute myeloid leukemia. Additionally, Kura Oncology presented promising data at the European Society for Medical Oncology Congress, showcasing the potential of its drug darlifarnib as a combination therapy. The clinical data indicated that darlifarnib, when combined with the multi-kinase inhibitor cabozantinib, showed objective response rates of 33%-50% in renal cell carcinoma patients. Analyst firm H.C. Wainwright reiterated a Buy rating with a $40 price target, emphasizing the enhanced antitumor activity of Kura’s farnesyl transferase inhibitor candidates in solid tumor patients. Citizens also maintained a Market Outperform rating with a $24 price target, highlighting the significance of Kura’s recent clinical presentations. These developments underscore the ongoing progress and interest in Kura Oncology’s research and potential treatments.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

Latest comments

Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers
© 2007-2025 - Fusion Media Limited. All Rights Reserved.