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Camurus AB reported its third-quarter 2025 earnings with a notable 18% increase in revenue, reaching 575 million SEK. Despite this growth, the company’s stock dipped by 6.97% to 547.5 SEK following the announcement. The company also adjusted its full-year revenue guidance downward to a range of 2.3 to 2.6 billion SEK, while maintaining its profit before tax guidance.
Key Takeaways
- Camurus reported a 43% profit margin with a 48% year-over-year increase in profit before tax.
- Product sales grew by 8% year-over-year, driven by the success of Buvidal/Brixadi.
- The company lowered its full-year revenue guidance but kept profit expectations unchanged.
- The stock fell nearly 7% post-earnings announcement, reflecting investor concerns over revised guidance.
Company Performance
Camurus demonstrated robust revenue growth in Q3 2025, with an 18% year-over-year increase, highlighting the strength of its product portfolio. The company’s performance was bolstered by its leading product, Buvidal/Brixadi, which achieved a 30% market share in the US long-acting buprenorphine market. However, the company faced challenges in the UK and Germany due to funding issues, affecting its overall market dynamics.
Financial Highlights
- Revenue: 575 million SEK (18% YoY increase)
- Product Sales: 455 million SEK (8% YoY increase)
- Profit Before Tax: 245 million SEK (43% profit margin, 48% YoY increase)
- Cash Position: 3.5 billion SEK (28% increase YoY)
Earnings vs. Forecast
Camurus reported earnings per share (EPS) that fell short of the forecasted 3.53 SEK. The company’s revenue also missed the forecast of 625.65 million SEK, coming in at 575 million SEK. This miss, combined with a lowered revenue guidance for the full year, contributed to the negative market reaction.
Market Reaction
Following the earnings announcement, Camurus’ stock price dropped by 6.97%, closing at 547.5 SEK. This decline reflects investor concerns over the company’s lowered revenue guidance and potential challenges in key markets. The stock is now trading closer to its 52-week low of 483.8 SEK, highlighting the market’s cautious sentiment.
Outlook & Guidance
Camurus has adjusted its full-year revenue guidance to a range of 2.3 to 2.6 billion SEK, down from previous estimates. The company maintains its profit before tax guidance between 0.9 to 1.2 billion SEK. Camurus is focusing on expanding its Buvidal/Brixadi markets and preparing for the launch of OxyESA in European markets.
Executive Commentary
Fredrik Tiberg, CEO, reaffirmed the company’s long-term vision, stating, "We still retain our vision for 2027, also in regards to the 100,000 patients." Richard Jameson, CCO, highlighted the company’s growth in Australia, noting, "Australia continues to grow well. We have about 30% share of the total market now."
Risks and Challenges
- Funding challenges in the UK and Germany could impact future growth.
- Market saturation in the US long-acting buprenorphine segment could limit expansion.
- Potential delays in product trials and market entries may affect timelines.
- Currency fluctuations pose a risk given the company’s international operations.
Q&A
During the earnings call, analysts raised questions about the funding challenges in the UK market and the competitive dynamics within the opioid use disorder treatment market. Executives also addressed concerns about the pricing strategy for OxyESA, confirming it at just under €3,000 per dose.
Full transcript - Camurus AB (CAMX) Q3 2025:
Fredrik Tiberg, CEO, Camurus: Welcome to Camurus Q3 Report 2025. During the Q&A, participants are able to ask questions by dialing #5 on the telephone keypad. Now I will hand the word over to CEO Fredrik Tiberg. Please go ahead.
Thank you so much, Einar, and hello everyone. Welcome to our third quarter earnings call. It is a beautiful autumn day here in Lund, Sweden, where we are sending this from. I will assume that you have read our forward-looking statements going forward here. The agenda for the call today is as follows. We start with third quarter highlights, move on to financial and commercial performance reviews, followed by an update on R&D, and then we will finish off with key takeaways and Q&A. With me on the call today is Anders Vadsholt, Chief Financial Officer, and Richard Jameson, Chief Commercial Officer. In the quarter, Camurus delivered strong profitability, continued progress of pipeline programs, and prepared for the launch of our next commercial product. Starting then here with some highlights.
On the financial side, our quarterly revenues increased by 18% year on year, 25% at constant exchange rate to SEK 575 million, driven by higher Brixadi royalties. Profitability remained strong, growing 48% to SEK 245 million, increasing our cash position to SEK 3.5 billion. We maintained our profit guidance. However, due to the headwinds we have had, we have lowered our full year revenue guidance. The commercial performance in the quarter was mixed, you could say. Overall sales in Europe slowed down temporarily, primarily due to ongoing funding issues, while Brixadi reported double-digit sales growth quarter to quarter. In parallel, we prepared for the launch of OxyESA in the European markets. This has been progressing very well. On the R&D side, marketing approvals for OxyESA were received in the U.K., and we also updated the NDA draft for the OKLAY submission.
This is pending completion of an inspection of the contract manufacturer. We were also granted two new orphan drug designations of CAM2029 in autosomal dominant polycystic kidney disease, and in addition, the treatment was completed in the phase 1B trial of our monthly semaglutide formulation, CAM2056. All in all, the third quarter has presented both challenges, but also very important successful developments and progress. With this, I leave the word over to Anders to review the financial performance of the quarter more in detail.
Anders Vadsholt, Chief Financial Officer, Camurus: Thank you, Fredrik. It’s a pleasure to provide the first financial update after joining Camurus in July. I’m generally pleased with the financial performance in the third quarter. Camurus reported SEK 567 million in revenue for the quarter, reflecting an 8% increase compared to the same period last year. Year to date, the reported revenue is SEK 1.8 billion, representing a 37% growth from previous years. Product sales reached SEK 455 million, an increase of 8% compared to the same period last year, but a decline of 3% compared to the previous quarter. We have experienced stable in-market growth throughout the year, but the distribution model has caused some deviations in the timing of revenue recognition. Brixadi sales in the US generated SEK 111 million in royalty income for the quarter, up 91% compared to the same period last year, and a 25% increase from the previous quarter.
The company’s profit before tax was SEK 245 million, representing a 43% profit margin in the quarter and a 48% increase in profit compared to the same period last year. The profit margin year to date is 45%. The profit after tax for the quarter was SEK 193 million, representing an earning per share after dilution of SEK 3.19. Moving to the P&L, the company’s gross margin was 93.1% for the quarter. Total operating expenditure was SEK 298 million, a 2% reduction compared to the same period last year. The main components were: we increased our investment in marketing and distribution by 27% to SEK 142 million to support market penetration, expanding Buvidal into new markets, and building our US operation. The recruitment of a US sales force has been aligned with the new timelines for the launch of OKLAY.
Administrative expenses increased by 49% to support company growth and development, mainly in the US, reaching SEK 40 million compared to the same period last year. Research and development investments were SEK 109 million, a reduction of 33% compared to the same period last year. This is mainly due to the completion of ArcGro Innova trials and the absence of clinical trial milestone payments in the Sorrento and Positano programs during the quarter. Looking at the cash flow for the quarter, Camurus increased its cash position by SEK 167 million, mainly driven by the operational activities, adding SEK 221 million, and proceeds from the employee stock option program, adding SEK 43 million. Working capital investments decreased cash by SEK 97 million, resulting in a net cash position of SEK 3.5 billion, which is an increase of 28% compared to last year. Moving to the update of the 2025 financial guidance.
Despite positive development in Brixadi and Buvidal, revenue did not live up to our previous expectations and guidance for the full year. This is primarily due to Brixadi US revenues below the previous projections, and there’s uncertainty about the timing of a sales milestone. In addition, we have seen continued delays in allocation of committed governmental funding for the treatment in the U.K. Importantly, our profitability has continued to develop positively with good financial discipline across the organization, and our planned US expansion has been aligned with the updated approval timelines for OKLAY. As a consequence, our restated full year 2025 outlook is as follows. Our revenue guidance is lowered to SEK 2.3-2.6 billion, and the profit before tax is unchanged in the range of SEK 0.9-1.2 billion.
Nevertheless, Camurus ended the first quarter with a healthy financial position, promising outlook for continued growth, profitability, and pipeline progress. With that, I would like to hand over to Richard.
Richard Jameson, Chief Commercial Officer, Camurus: Thank you, Anders. I’ll start with the Camurus market. Net sales for Buvidal in the quarter were SEK 455 million, up 8% year on year, or 15% at constant exchange rate. Versus Q2, sales were down 3%, primarily due to the lower-than-expected orders in the U.K., which also led us to reduce inventory levels. In contrast, underlying in-market sales grew 3% versus Q2 and are 21% year to date, driven by maintained growth in Australia, Norway, France, and Spain as we continue to execute on our plans, while we saw flattening of growth in the U.K. and Germany due to two main factors. In the U.K., there are ongoing delays in allocated funding reaching community clinics. However, growth began to accelerate in the criminal justice setting as allocated NHSE funding for long-acting injectable buprenorphine treatment in prisons has become available.
In Germany, resistance to uptake remains due to the ongoing remuneration of physicians based on daily visits. Year to date, in-market growth is positive, around 20% across markets, with the exception of Finland, where growth was single-digit due to the high penetration we have there. There continues to be high demand from patients and physicians for long-acting injectable buprenorphine, and we continue to support this through active programs that build awareness of the benefits the product brings to patients and wider society. This, in turn, is increasing demand for wider accessibility and is expected to deliver renewed growth in 2026. On the next slide, I share more detail of our ongoing strategy for improving patient access. We are continuing to grow the real-world evidence base and develop economic models that demonstrate the improved outcomes and the value long-acting buprenorphine brings over daily treatments.
The economic models, of which there are some publications on the left-hand side of the slide, clearly demonstrate the positive value of treatment with an AIB, typically showing a more than three-time return for governments. These data and models are a critical part of our initiatives to improve access through a government affairs program that is engaging a wide group of policy stakeholders who will benefit from improved access to these innovative treatment options. As a result of these programs, we are seeing growing demand in criminal justice settings and the need for the community continuity of care on release, alongside support to address funding in community settings. This has already resulted in some success, including allocation and distribution of funding from the criminal justice setting in the U.K. that I mentioned earlier, and regional funding expansion in France.
We also understand good progress is being made on alternative remuneration models in Germany that will address this key hurdle for Buvidal. The success of this activity is critical to expand the use of Buvidal in these markets in 2026. Now moving across to the U.S., Brixadi had a strong quarter, as you’ve already heard, with royalties growing 25% versus previous quarter and 91% year on year. Brixadi continues to outgrow the market and has reached an approximate 30% share of the long-acting buprenorphine segment, which in itself is growing 25% year on year and for the first time reached annualized sales of $1 billion. In the U.S., Brixadi represents a significant opportunity for future growth through penetration of the sublingual buprenorphine market, with an estimated 1.8 million patients in treatment and with further potential in the criminal justice setting.
Brixadi has a clear and differentiated profile, and Braeburn are successfully navigating the challenges in the OUD treatment market. Overall, we remain optimistic about the prospects for Brixadi in the US and the potential for significant growth in the coming years. On this, I’ll hand back to Fredrik.
Fredrik Tiberg, CEO, Camurus: Thank you, Richard. Let’s move over to a quick pipeline update. Starting with the progress of the octreotide depot programs for acromegaly, gastroenteropancreatic neuroendocrine tumors, GEPNET, and polycystic liver disease, PLD. As you know and have heard before, we have a large clinical program for CAM2029, which represents a major investment and a future potential for Camurus. In acromegaly, we have successfully completed the ArcGro Innova program, delivering positive results from two pivotal phase III trials, as well as a long-term extension study. In GEPNET, we advanced the Sorrento trial towards the important readout of the primary efficacy results in 2026. Finally, we recently completed the Positano study in PLD, also with positive results for the primary endpoint. I will start here with an update of the Sorrento study in GEPNET.
This was recently discussed at a well-attended scientific symposium at the North American Neuroendocrine Tumor Society meeting in Austin, Texas, where it rendered significant attention among the participating physicians and other healthcare providers. The topic of the symposium was dose optimization of somatostatin receptor ligands, which is the efficacy driving hypothesis behind the Sorrento trial. Chair of the symposium was Dr. Jennifer Chan, president of NANETS, and presenter was Simran Singh, University of Toronto, who is the president-elect of NANETS, actually now the president of NANETS. Both are Sorrento study investigators and steering committee members. The conclusion of this discussion was that there are very high hopes and good prospects for Sorrento and CAM2029, of course providing positive outcomes. Patient recruitment in Sorrento was started already in Q4 2021.
Which means that the first enrolled patients have now been in treatment for about four years, in many cases without disease progression. The study was fully recruited at the end of 2023, as all patients have been assessed for about two years or longer. So far, the experiences from the trial are generally very positive in terms of patient feedback, and the projections for completing the randomized efficacy part of the trial have been extended based on the lower than predicted rates of progression-free survival events during the past few months. We recently completed a new analysis of the accrual rates in the study, and based on the trends, we have updated the projections for reaching the 194 events for the study to mid or second half of 2026. From a CAM2029 and study outcomes perspective, the adjustment should be positive, while also extending the time to primary results.
To put this in perspective, I would like to highlight the study design and patient population that is part of the Sorrento trial. Compared to previous studies of tumor progression, Sorrento is a randomized active control study with a primary objective to assess the superiority in progression-free survival for treatment with CAM2029 versus standard of care with first-generation somatostatin receptor ligands. It is indeed the largest-ever study of SRL performed in patients with neuroendocrine tumors. A majority, and this is an important point, of the patients in Sorrento has advanced grade two or grade three neuroendocrine tumors at baseline compared to no or a minor portion of patients in the earlier tumor control trials, Promid and Clarinet. The progression-free survival for the blinded population in Sorrento should be viewed in the context of the study population, which makes us optimistic about the study prospects.
Moving over to PLD, during the quarter, we continued analyzing data from the Positano trial in preparation for an end-of-phase two meeting with the FDA planned for early next year. Furthermore, CAM2029 was granted orphan drug designation for autosomal dominant polycystic kidney disease, ADPKD, both in the US and EU during the period, pointing to the high unmet medical need in this indication. Importantly, this can also expand the future orphan drug exclusivity to PLD arising from ADPKD. That is significant progress in itself. Finishing off with the acromegaly indication, OxyESA has now been granted market authorization for the treatment of acromegaly in both EU and the U.K. For the US, the NDA has been updated during the quarter and is ready for resubmission as soon as we have received green light from an inspection at the contract manufacturer.
Please remind yourself that there was nothing in the CRL from the FDA that was related to the product itself or its clinical or safety data. Based on our plans for resubmission, we expect a new PDUFA date and a potential US launch of OKLAY in the first half of 2026. This will, of course, be an important event for us. In parallel, we are preparing for launches of OxyESA in Europe, the first monthly subcutaneous octreotide medication in the market, enabling convenient self-administration for patients and enhanced octreotide plasma exposure. The European launch has now been initiated in the wave one countries with an estimated 3,000-5,000 acromegaly patients currently treated with first-generation long-acting somatostatin receptor ligands. The response to the OxyESA profile from physicians and patients has so far been very encouraging, with a positive view both on this and clinical data.
Market research that we have performed in the area shows a high willingness to switch to OxyESA from current somatostatin receptor ligands. In addition to this, we have also had positive initial feedback from payers. As you may have seen from the announcement earlier this week on Monday, OxyESA has now been launched in Germany as the first country in Europe and globally, and our medical affairs and sales team are now out in the field. Germany represents a substantial opportunity with about 2,000 patients currently in treatment with first-generation somatostatin receptor ligands and with an annual sales potential of over EUR 50 million. A recently performed physician survey suggests that about 30%-60% of these patients are initially considered suitable for switching to OxyESA. Obviously, GEP-NET represents a much larger opportunity. However, acromegaly is, of course, a great starting point here.
Alongside the advances of the CAM2029 program, we have also completed treatment of the last patient in the phase 1B study of our monthly semaglutide formulation, CAM2056, based on our FluidCrystal technology. We now expect to provide top-line results this month with focus on tolerability and, of course, importantly, efficacy indicators such as body weight and HbA1c. In addition, we progressed our strategic partnership with Eli Lilly for the development and commercialization of long-acting incretins in the cardiometabolic area, including GLP-1/GIP dual agonists and GLP-1/GIP/glucagon triple agonists. We are naturally very excited about progressing this collaboration. I think it’s time to finish off with some key takeaways of the quarter. In summary, we had a good quarter. As you have heard, not without challenges. However, we did significant advances and progressed and expanded our business, delivering strong profitability and cash flow.
Stable Buvidal sales in Europe and Australia. I think our team is doing an excellent job also with regards to the future development in the market. Notably, Brixadi had another good quarter in the US, outgrowing the rest of the market. In addition, for OxyESA in acromegaly, we received the UK approval and prepared the launch in Germany. Also, as I mentioned recently here, we advanced our promising long-acting incretin pipeline. With this final note, I think it’s time now to move over to Q&A. Please, Einar, take over the call. Thanks, Fredrik. The first question is from Viktor Sundberg from Nordea. Please go ahead, Viktor. Line is open.
Anders Vadsholt, Chief Financial Officer, Camurus: Yes, hi. Thanks for taking my questions. I had a question first on Buvidal. I just wondered if you could provide any more details when you expect funding to be released to clinics and when the market could turn around in the U.K. I mean, I was trying to get a feel for if this could spill over into Q4 as well or into early 2026 or how we should model this impact. Thank you.
Fredrik Tiberg, CEO, Camurus: Yeah, I will leave that over to Richard too.
Richard Jameson, Chief Commercial Officer, Camurus: Yes, I mean. Funding is coming in drips and drabs. There are some areas that are having funding now, others less so. I can’t guess what the government would do, but we hopefully will see some advances in Q4 and then moving into 2026 as well on that. I mean, it is growing, the U.K. market. We are getting more patients. It’s just slower than we anticipated.
Anders Vadsholt, Chief Financial Officer, Camurus: Okay, thanks. I had a question as you have launched OxyESA now in Germany. Could you comment maybe how it’s priced versus the other injectable depot formulations on the market? Thank you.
Fredrik Tiberg, CEO, Camurus: Yes, I think you could estimate that it’s priced at the high end of the somatostatin reference product.
Anders Vadsholt, Chief Financial Officer, Camurus: Okay.
Fredrik Tiberg, CEO, Camurus: Just. I think it’s the official price now.
Richard Jameson, Chief Commercial Officer, Camurus: It’s just under EUR 3,000.
Fredrik Tiberg, CEO, Camurus: Yeah, just under EUR 3,000 per dose.
Anders Vadsholt, Chief Financial Officer, Camurus: Okay, yeah. Okay, thank you very much. That’s all for me.
Fredrik Tiberg, CEO, Camurus: Next. Hello?
Hi, Katie. Can you hear me?
Yes, we hear you.
Cool. A couple of questions on my end. The first one is for Buvidal in Europe. How many net patient additions were there in Q3? Are there any additional markets that recently came into play? For example, think of Portugal. That can support future growth while the issue in the U.K. and Germany persists.
Yeah, certainly. I mean, we reported a number of patients, 67,000, but Richard, maybe you can comment on the growth in the additional markets, Spain and.
Richard Jameson, Chief Commercial Officer, Camurus: Yes, I mean, everybody making a contribution. We grew 2,000 patients between quarters this time. Portugal, yes, is ready to come on. It’s early days in that market, so we’re waiting to see that. Yes, they will provide an opportunity for us as we move forward to grow the numbers of patients in treatment.
Fredrik Tiberg, CEO, Camurus: We are seeing the positive trends also in Spain, where we are seeing big potential. Of course, we have further countries, including the northern European part. Maybe this should also be put into the context of the dynamics of other movements in the Nordic markets and elsewhere. It looks there is good growth potential.
Okay, got it. Thank you. Maybe another one on Brixadi in the US. At last update, I think it was around Q4 last year, the numbers showed roughly 25% market share for Brixadi in the LAI markets. Now it stands at 30%. Is this the market share of new patients switching from sublingual buprenorphine to LAI?
I think, I mean, the main component, and we have talked about that for quite some time, is that most patients are coming from sublingual buprenorphine, of course. Depending on the relative growth in that segment, this will, of course, impact the market share between different products. I would say the majority of the share is coming straight from sublingual.
Okay, I mean, the reason why I’m asking this is last week Indivior reported a 75% market share. So we’re just wondering on which metric you based this 30% market share.
We have done, used several different metrics, we should say, or different data sources, and all of them converge into 30%. That includes both.
Okay, got it.
Public sources and also other sources that we have access to.
Okay, thank you very much. That’s all for me.
Einar, Call Moderator, Camurus: Sorry, the next question is from Richard Ramanius from Redeye. Please go ahead. Please go ahead, Richard.
Hello, good afternoon. Yes, I had two questions on the guidance for this quarter. I’ll just read both questions straight away. In your Q3 report, you guided for around SEK 650 million R&D costs in 2025. Also, this was dropped in the Q3 report. Is this because you expect costs will be lower this year? Is this because you overestimated costs or because some costs will be postponed into 2026? My second question is you lowered the guidance, should we say, implicitly from Braeburn since you don’t expect the milestone, which I assume is revenue-based. Is that because of stronger US competition or other market dynamics or both?
Anders Vadsholt, Chief Financial Officer, Camurus: Yeah, so. Shortly, so we’re not pushing costs ahead of us. Of course, there will be something that is a bit delayed, but there’s also been a number of savings in the R&D department. We’re doing a tech transfer and so on. So it is cost reductions, and then some of the costs will come into 2026. It’s a mixed situation here, but it will be lower for the year.
Okay, yeah, that’s good to hear.
Fredrik Tiberg, CEO, Camurus: Can you repeat that? I missed the second question. Sorry for not answering that.
Yeah, sure, no problem. Implicitly, you guided for lower revenue from Braeburn since you do not longer assume a milestone payment, which I assume is related to revenues. Is that because of stronger US competition or just because of market dynamics?
I think it’s mainly market dynamics. I mean, we were expecting. We had, of course, very high expectations on the year, and those have come gradually down. I think the good news is that we have seen very good recovery here, especially now also consistent recovery. In total, this has led to the milestone being at risk, which, of course, it was not in the early phase of our assessment.
Okay, that was my two questions. Thanks.
Thank you.
Einar, Call Moderator, Camurus: The next question is from Sean Harmer from Jefferies. Please go ahead.
Fredrik Tiberg, CEO, Camurus: Hello, Sean.
Einar, Call Moderator, Camurus: I think actually it’s Romy O’Connor.
Fredrik Tiberg, CEO, Camurus: Oh, yeah.
Einar, Call Moderator, Camurus: You dropped Sean. Sean, if you can queue up again.
Yes.
Fredrik Tiberg, CEO, Camurus: Hello, Romy.
Hello. I have one question. I was wondering if you could provide more color on your manufacturing expansion efforts in the US. I know you’re planning further investments to deploy US operations for acromegaly. I’m just wondering what your thinking is for GEPNET next year and what your sales force will look like there. Thank you.
Yeah, I mean, in terms of manufacturing, we have talked about that last quarter. All of those processes are advancing. Obviously, we have our current sources, but we have a need to secure future supplies, especially then when GEP-NET comes up. That is an important part of the further development of GEP-NET. That is progressing perfectly according to plans. That is, yeah, positive.
Just maybe one more quickly. I was just wondering if you could share a bit on your future outlook for the Australian market with Buvidal, because now you’ve reached 80% share, I think, of the LAI buprenorphine market. Do you think this is reaching a plateau, or do you see future growth here?
Richard?
Richard Jameson, Chief Commercial Officer, Camurus: Yes, I mean, Australia continues to grow well. We have about 30% share of the total market now, as you said, above 80% of the long-acting segment. We still see that demand in Australia. We still see it growing. There is a lot of people still on sublingual that are interested in moving across. Of course, methadone is a large segment as well. We are seeing increasing numbers moving across from methadone because of the advantages long-acting brings. We anticipate continued growth in Australia.
Okay, clear. Thank you.
Einar, Call Moderator, Camurus: Now we have Sean Harmer from Jefferies. Please go ahead.
Fredrik Tiberg, CEO, Camurus: Hello, Sean.
Hi there. Thanks. Hi, Fredrik. Just two questions from me. I’ll take them one at a time. On the Sorrento readout, obviously, we know this has been pushed to sort of late 2026. It makes sense that this is because of the time to recruit events, but are there any concerns that the control arm may be outperforming, such as, for example, when Ivo Bruton’s phase three study read out and Obaggio surprisingly outperformed?
I mean, you can never come with guarantees on these things. In terms of, obviously, we are using the literature reference data. We are trying to compensate for populations and population characteristics and so forth. There is nothing new that has happened in terms of the standard of care changing in terms of treatment changes and so forth. I think we should. This should not be the case, but you can never be sure 100%. I think our view on this is, and that’s also our physicians’ input, is that there has not been any material changes into the treatment regimen for the standard of care. It is about trying to understand the different data sources. I think we have a good indication.
Understood. Thank you. For my second question, could you just tell us what Braeburn’s communicated with respect to the criminal justice channel and the dynamics that will occur during 3Q on both state and federal side, and then what would it look like before Q?
I mean, that leaves me with, I’m sorry, but because of the competitive situation, but also because of our contractual situation, I’m not able to go into any details on this note at this moment, Sean. I would, of course, want to, but I cannot fill you in on this.
No, that’s fair. Thank you, Fredrik.
Thank you.
Einar, Call Moderator, Camurus: The next question is from George Tigalono Bjarke from ABG. Go ahead, George.
Hi, guys. George here. Thank you for taking my questions. I have a couple. First, I was wondering whether you or Braeburn have seen any price pressure for Buvidal or Brixadi lately. Secondly, your competitor, Indivior, for example, at their Q3 reporting last week, they highlighted that Sublocade as a unique offering in the long-acting release category in terms of rapid induction, i.e., a second monthly dose injection after one week. Indivior has a history of quite aggressive marketing. I’m curious if you’re able to comment whether or not you think this is an actual significant distinguishing factor versus Brixadi, seeing as Brixadi allows for weekly initiation with the weekly dose injections. Thank you.
Fredrik Tiberg, CEO, Camurus: Thank you so much. To the first question about price, I don’t think we have heard about any price pressure in the US. I mean, obviously, the whole system has. Price is an increasingly important component. I haven’t heard of anything specific there or anything that is concerning to us. When it comes to the rapid initiation with Indivior’s product, I don’t prefer to kind of make judgments versus a colleague in the market here. I think it probably has some advantages for them. I think we have a very good treatment regimen as it is. We have the transfer doses from sublingual, which is the most important market process. We have the weekly start, so we have all of this under control. There was a big study conducted in emergency centers in the US with over 2,000 patients using the weekly start as a very.
Successful measure to take over patients from in-hospital treatment to outpatient treatment. Plus, it’s used very regularly in the system. Do you have any further to say there, Richard?
Richard Jameson, Chief Commercial Officer, Camurus: Yeah, to add to that, I mean, some of the feedback from some of the qual research we’ve seen from various groups is that patients like to start with weekly because they want to understand how it feels to be like on a long-acting before they commit fully to a monthly treatment. I think the patient preference is for a weekly initiation. Our experience in Europe shows that.
Fredrik Tiberg, CEO, Camurus: I think most, yeah, and most importantly, of course, we still see that we have, I mean, it appears that our partner is doing a good job in the US. We are progressing. CAM2029. Sorry, 38 it was. But we’re progressing Brixadi nicely in the US based on our competitive profile. I think that holds a lot of advantages compared to other products in the market. Thank you for the question.
Einar, Call Moderator, Camurus: Thanks. The next question is from Susanna Kwek-Bonner from Handelsbanken.
Hello, Susanna Kwek-Bonner here, Handelsbanken. I have another question on Buvidal. You have your target for 2027 of reaching 100,000 patients. With the last few quarters of 2,000 patients net addition, you need to substantially accelerate to reach that going forward. Perhaps you could comment on how you think about that. Also, is that possible in the markets that you currently have, or will you need to address the regions where we’ve had budget constraints differently?
Fredrik Tiberg, CEO, Camurus: Yeah, first, I mean. We still retain our vision for 2027, also in regards to the 100,000 patients. Obviously, there are challenges and opportunities. Maybe, Richard, you want to go into your thinking around this?
Richard Jameson, Chief Commercial Officer, Camurus: Yes, I mean, it’s not necessarily a linear approach. As we create successful arguments to increase access, we can see acceleration there. We’ve got a number of processes that are ongoing. In discussions with various groups that could still bear fruit to that. Our ambition is still achievable. I think we have to remember that. We still have relatively low penetration in this market at about 10% of patients. There’s still plenty of opportunity to grow the business. We can if we can resolve the funding issues and the hurdles we faced, which we’re on track to do.
Fredrik Tiberg, CEO, Camurus: I think adding to that, I mean, obviously, we have great teams working in various different everything from government affairs to direct contacts with the medics and so forth. We generally have a very positive field. As Richard says, it will not be a linear curve up to the goal. It will be a lot of hard work. We retain our vision, and we are working hard to achieve it.
Very good. Then a follow-up on the Eli Lilly deal. In the initial press release, you did not mention anything regarding Amylin, but there was opportunity to expand. Can you maybe just give us a little bit more on what progresses have been made recently and how you think about other increments?
I can’t give you any update because it’s outside my remit, so to speak. Yeah, I mean, obviously, they have an option to Amylin. Usually, an option has a time limitation coupled to it. That’s one of the components of our collaboration, which I think you can very nicely say that right now it’s progressing very well. I can’t give you any details on that beyond those two comments.
Okay, thank you very much.
Thank you, Susanna.
Einar, Call Moderator, Camurus: The next one’s from Dan Akshooti from Pareto Securities.
Fredrik Tiberg, CEO, Camurus: Hello, and just one more question. That is regarding 2056 as well. If you can share just some more details that you’re expecting from the data readout this month and what you will be able to share in terms of detail of the data. Will it be just a press release with some top line, or will you share a lot of graphs and details on GKPD, etc.? Thank you. Thank you. Yeah, first of all, I think it’s important to know the study design. Basically, the study design is one part which is a randomized part versus semaglutide, so the monthly versus the weekly. There is a second part of the study, which is basically a dose escalation part, so we’re going from low to high concentrations or very high concentrations. Obviously, we will report comparative data, focusing on the.
Obviously, tolerability profile is important, weight, and PD readouts in terms of HbA1c and so forth. The traditional measures, it will most likely be provided in a press release form with some data points, key data points. Later on, we’ll likely follow up with more detailed information about the product results. I think that’s the order of them. What is unique with this study is, of course, that we have an active comparator. I think it’s not that usual that you go into a phase 1B study with an active comparator. It will be an interesting readout from the study with, I think, clear potential to demonstrate something of relevance. That’s how far I can. Thank you very much.
Einar, Call Moderator, Camurus: We have a follow-up from Sean Harmon from Jefferies as well.
Fredrik Tiberg, CEO, Camurus: Again, Sean?
Hey, just one more from me really quickly. Can we expect CAM2056 to be press released this month then? Could you just speak to how detailed that release will be? I know it’s only phase one, but any sort of color would help. Thank you.
Yeah, I mean, absolutely, our intention is, according to the current timelines and so forth, our intention is to be able to press release it this month. The data, I mean, I think you can anticipate about the same level of detail as you see from other pharmaceutical companies working in the space for a phase 1B trial or early phase 2 trial. I think that you should expect that level of detail approximately.
Thanks so much.
Yeah, thank you.
Einar, Call Moderator, Camurus: There are no more questions at this time. So I hand the word back to you, Fredrik, Anders, and Richard, for closing comments.
Fredrik Tiberg, CEO, Camurus: Okay, thank you so much. I just want to say it’s, of course, we thank you very much for joining into this call. It’s a pleasure to have interest from you all and engaging questions. I look forward to meeting you all on the road or at our next call in Q4, the Q4 report. With that said, thank you again, and we can close the call.
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