Cantor Fitzgerald maintains Overweight on GlycoMimetics stock

Published 21/03/2025, 12:28
Cantor Fitzgerald maintains Overweight on GlycoMimetics stock

On Friday, Cantor Fitzgerald reaffirmed an Overweight rating on GlycoMimetics (NASDAQ:GLYC), a small-cap biotech with a market capitalization of $17.5 million. According to InvestingPro data, the stock has shown significant volatility, with a 65% surge over the past six months despite a 90% decline over the past year. The company’s strategic move to merge with Crescent is expected to be finalized in Q2. The analyst highlighted Crescent’s primary asset, CR-001, a preclinical VEGF x PD-1 bispecific therapy, which follows the model of Summit’s ivonescimab. Ivonescimab has shown promise, particularly in demonstrating superior progression-free survival (PFS) against pembrolizumab in first-line non-small cell lung cancer (NSCLC).

The analyst noted that ivonescimab is currently undergoing multiple pivotal trials for lung cancer on a global scale and in various other tumor types within China. The potential of ivonescimab and the VEGF x PD-(L)1 bispecific class has garnered significant attention in the industry, with the belief that ivonescimab could become a blockbuster drug.

GlycoMimetics’ CR-001 is considered a competitive "fast follower" to ivonescimab, with the potential to be rapidly de-risked and to capture a substantial market share in what could be a market exceeding $100 billion for VEGF x PD-(L)1 bispecifics. The analyst’s optimism about CR-001’s prospects and the potential market size underpins the Overweight rating on GlycoMimetics stock.

The merger between GlycoMimetics and Crescent is anticipated to bring together significant resources and expertise, potentially accelerating the development of CR-001. InvestingPro analysis reveals the company maintains a healthy current ratio of 1.92 and holds more cash than debt on its balance sheet, though it’s currently experiencing rapid cash burn. The deal is viewed as a strategic step for GlycoMimetics in positioning itself within a highly lucrative segment of the cancer treatment market. Get access to 10 more exclusive InvestingPro Tips and comprehensive financial analysis with a subscription.

Investors will be closely monitoring the progress of the merger and the subsequent development of CR-001 as GlycoMimetics aims to capitalize on the growing interest in bispecific therapies for cancer treatment. With analyst price targets suggesting significant upside potential and a beta of 1.81 indicating higher market sensitivity, the stock warrants careful attention. With the closing of the merger expected in the second quarter, GlycoMimetics is poised to enter a new phase of growth and development in the biopharmaceutical industry. Dive deeper into GlycoMimetics’ potential with InvestingPro’s exclusive research report, part of our coverage of 1,400+ US stocks.

In other recent news, GlycoMimetics Inc. has announced several key developments impacting its operations and strategic direction. The company disclosed the termination of a significant agreement with Apollomics, which ends their collaboration and license agreement for two drug candidates in specific Asian markets. This termination will take effect after a 90-day notice period, leaving GlycoMimetics with no material financial obligations related to the contract. In addition, the company has made changes to its leadership, with the resignation of several board members and executives, including CEO Harout Semerjian and CFO Brian Hahn, who will continue as consultants during the transition.

Furthermore, GlycoMimetics has amended its merger agreement with Crescent Biopharma, adjusting the financing structure but maintaining the previously anticipated exchange ratio. Post-merger, Crescent security holders are projected to own a majority of the combined entity. In another development, GlycoMimetics was granted an extension to meet Nasdaq’s minimum bid price requirement, with a deadline set for June 16, 2025. The company is considering options, including a reverse stock split, to address the deficiency and maintain its Nasdaq listing.

These recent developments come as GlycoMimetics navigates significant corporate changes and prepares for its proposed merger with Crescent Biopharma.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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