ALXO stock plunges to 52-week low of $0.48 amid market challenges

Published 10/04/2025, 15:56
ALXO stock plunges to 52-week low of $0.48 amid market challenges

In a stark reflection of the volatile market conditions, Alx Oncology Holdings Inc. (ALXO) stock has tumbled to a 52-week low of $0.48, with the current price at $0.49. According to InvestingPro analysis, the stock is trading below its Fair Value, with analyst price targets ranging from $1.50 to $5.00. This significant downturn has reduced the company's market capitalization to just $26.69 million, with the stock declining by 95.7% over the past year. Investors have been closely monitoring ALXO as it navigates through a challenging phase, marked by investor skepticism and broader market headwinds that have pressured the biotechnology sector. InvestingPro data reveals a weak overall financial health score, though the company maintains a strong current ratio of 7.26. The 52-week low serves as a critical indicator of the hurdles the company faces, as it struggles to regain its footing in a competitive and rapidly evolving industry landscape. The stock's Price/Book ratio of 0.24 reflects the market's current pessimistic outlook on the company's prospects.

In other recent news, ALX Oncology has announced the U.S. Food and Drug Administration (FDA) clearance for an Investigational New Drug application for ALX2004, aimed at treating solid tumors expressing the epidermal growth factor receptor. The company plans to initiate Phase 1 clinical trials in mid-2025. In addition, ALX Oncology has disclosed a strategic workforce reduction of approximately 30% to prioritize its product pipeline and conserve cash, with completion expected by May 2025. The departure of President and Chief Scientific Officer, Dr. Jaume Pons, is part of this reorganization.

Analyst opinions on ALX Oncology have varied recently. Stifel has reduced its price target to $1.50 while maintaining a Hold rating, citing concerns over development strategies and regulatory risks. Meanwhile, Jefferies has upgraded the stock to Buy, raising the price target to $3.00, based on a favorable risk/reward assessment. UBS has also adjusted its price target to $2.20, down from $4.00, but retains a Buy rating, noting the need for further investigation into the efficacy of evorpacept in HER2-positive gastric cancer. These developments reflect the ongoing strategic adjustments and varied analyst perspectives on ALX Oncology's prospects.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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