Ionis Pharmaceuticals stock hits 52-week high at 64.89 USD

Published 30/09/2025, 15:54
Ionis Pharmaceuticals stock hits 52-week high at 64.89 USD

Ionis Pharmaceuticals Inc. stock reached a 52-week high, trading at 64.89 USD. This milestone reflects a significant upward trajectory for the company, which has seen its stock price increase by 66.11% over the past year. The biotechnology company, now valued at $10.3 billion, has delivered an impressive 112.6% return over the past six months, with InvestingPro data showing a robust 83.5% year-to-date gain. The biotechnology firm, known for its innovative RNA-targeted therapies, has captured investor interest, contributing to its impressive performance in the stock market. This 52-week high underscores the market’s growing confidence in Ionis Pharmaceuticals’ potential and strategic direction. According to InvestingPro, the company maintains strong financial health with a current ratio of 2.87, though technical indicators suggest the stock may be in overbought territory. Discover 10+ additional exclusive insights and comprehensive analysis available in the Pro Research Report.

In other recent news, Ionis Pharmaceuticals has been the subject of several noteworthy developments. The company reported positive topline results from a pivotal study of zilganersen, its treatment for Alexander disease, which demonstrated statistically significant improvements in gait speed and other secondary endpoints. This news has led multiple analyst firms to adjust their outlook on Ionis. Goldman Sachs upgraded Ionis from Sell to Neutral, citing the optimization of its antisense oligonucleotide technology and positive data from its Tryngolza Phase 3 trial in severe hypertriglyceridemia.

Additionally, Leerink Partners raised its price target for Ionis to $68, maintaining an Outperform rating, following the release of the zilganersen trial results. Guggenheim also increased its price target to $92, while keeping a Buy rating, due to the positive Phase 3 data for Alexander disease treatment. H.C. Wainwright reiterated its Buy rating with a $95 price target, highlighting the disease-modifying benefits of zilganersen. These developments reflect growing optimism among analysts regarding Ionis Pharmaceuticals’ pipeline and clinical trial outcomes.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

Latest comments

Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers
© 2007-2025 - Fusion Media Limited. All Rights Reserved.