Silence Therapeutics stock hits 52-week low at $2.35 amid market challenges

Published 07/04/2025, 16:18
Silence Therapeutics stock hits 52-week low at $2.35 amid market challenges

In a challenging year for biotech firms, Silence Therapeutics (SLN) stock has tumbled to a 52-week low, touching down at $2.35. The company, known for its work in the field of gene silencing, has faced a tough market environment, with its market cap shrinking to $127.5 million. According to InvestingPro data, the stock has seen a steep decline of -87.66% over the past year, though analyst targets range from $4 to $75. Investors have shown concern as the stock plummeted from higher valuations, reflecting broader industry trends and internal hurdles. While the company maintains a strong liquidity position with a current ratio of 11.14 and more cash than debt, InvestingPro analysis suggests the stock is currently undervalued, with 11 additional ProTips available to subscribers. The current price level marks a critical juncture for Silence Therapeutics as it navigates through a period of heightened scrutiny and strategic reassessment, with its next earnings report due on May 15, 2025.

In other recent news, Silence Therapeutics reported a significant increase in revenue for 2024, reaching $43.3 million, up from $31.6 million in 2023. This growth was largely driven by strategic collaborations with AstraZeneca (NASDAQ:AZN) and Hanseo Pharma. The company also revealed a strategic decision to delay the phase 3 trial of their drug candidate zerlasiran until a partnership is secured, extending their cash reserves to support operations into 2027. Analysts from H.C. Wainwright maintained a Buy rating with a $75 price target, citing potential catalysts such as partnership announcements for zerlasiran. Meanwhile, Morgan Stanley (NYSE:MS) adjusted its price target to $45, reflecting updates to the company's financial model and a reduced probability of success for zerlasiran. Jefferies also slightly lowered its price target to $30, maintaining a Buy rating. Silence Therapeutics is advancing its pipeline with plans to initiate a phase 1 trial for SLN548 in the second half of 2025, further expanding its portfolio of RNAi therapies.

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