Silence Therapeutics PLC (SLN)

Currency in USD
5.04
-0.34(-6.32%)
Closed·
After Hours
5.040.00(0.00%)
·
SLN Scorecard
Full Analysis
Holds more cash than debt on its balance sheet
SLN is not included in our AI-picked strategies. See which stocks are.
Fair Value
Day's Range
5.025.50
52 wk Range
1.9720.48
Key Statistics
Prev. Close
5.38
Open
5.25
Day's Range
5.02-5.5
52 wk Range
1.97-20.48
Volume
68.89K
Average Volume (3m)
116.36K
1-Year Change
-68.01%
Book Value / Share
2.39
Fair Value
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Fair Value Upside
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SLN Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
32.37
Upside
+542.21%
Members' Sentiments
Bearish
Bullish
ProTips
Quickly burning through cash

Silence Therapeutics PLC News & Analysis

Show more

Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Sell
Technical Indicators
Strong Sell
Moving Averages
Strong Sell

Silence Therapeutics PLC Company Profile

Silence Therapeutics plc, a biotechnology company, engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. The company develops Zerlasiran (SLN360), which is in Phase II clinical trial for cardiovascular disease associated with elevated lipoprotein(a); Divesiran (SLN124), an siRNA molecule that is in Phase I clinical trial for the treatment of genetic hematological conditions, including polycythemia vera; and SLN548 for complement-mediated disease. Silence Therapeutics plc has collaboration agreements with AstraZeneca PLC to discover, develop, and commercialize siRNA therapeutics for the treatment of cardiovascular, renal, metabolic, and respiratory diseases; and Hansoh Pharmaceutical Group Company Limited to develop siRNAs. The company was formerly known as SR Pharma plc and changed its name to Silence Therapeutics plc in May 2007. Silence Therapeutics plc was incorporated in 1994 and is headquartered in London, the United Kingdom.

Silence Therapeutics PLC SWOT Analysis


RNA Frontie
Explore Silence Therapeutics's position in RNA therapeutics, focusing on cardiovascular and hematological disorders with promising clinical results
Zerlasiran's Potential
Delve into Zerlasiran's market opportunity, with analysts anticipating 50-100%+ stock upside upon partnership announcement
Divesiran Breakthrough
Learn about Divesiran's impact on Polycythemia Vera treatment, reducing phlebotomy needs and garnering significant partnership interest
Financial Outlook
Analysts project $30M revenue for 2024-2025, with price targets ranging from $67 to $75, despite current trading near 52-week low of $4.82
Read full SWOT analysis

Silence Therapeutics PLC Earnings Call Summary for Q4/2024

  • Revenue increased to $43.3M in 2024 from $31.6M in 2023, driven by strategic collaborations with AstraZeneca and Hanseo Pharma
  • Net loss reduced to $45.3M in 2024 from $54.2M in 2023; cash reserves of $147.3M extend runway into 2027
  • Stock rose 5.24% premarket despite 81% decline over past year; analysts set price targets from $6 to $75
  • Company plans to secure partner for Zolaciran Phase 3 study and complete Divisiran Phase 2 enrollment by year-end
  • Management optimistic about ongoing partnership discussions and positive regulatory feedback for upcoming trials
Last Updated: 27/02/2025, 15:08
Read Full Transcript

Compare SLN to Peers and Sector

Metrics to compare
SLN
Peers
Sector
Relationship
P/E Ratio
−3.0x−2.6x−0.5x
PEG Ratio
0.04−0.090.00
Price/Book
2.5x2.7x2.6x
Price / LTM Sales
8.8x9.7x3.3x
Upside (Analyst Target)
-266.1%43.4%
Fair Value Upside
Unlock14.6%7.1%Unlock

Analyst Ratings

6 Buy
0 Hold
1 Sell
Ratings:
7 analysts
Overall Consensus
Buy

Analysts 12-Month Price Target:

Average 32.37
(+542.21% Upside)

Earnings

Latest Release
Aug 07, 2025
EPS / Forecast
-0.19 / -0.1323
Revenue / Forecast
224.00K / 6.93M
EPS Revisions
Last 90 days

SLN Income Statement

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FAQ

What Stock Exchange Does Silence Therapeutics Trade On?

Silence Therapeutics is listed and trades on the Nasdaq Stock Exchange stock exchange.

What Is the Stock Symbol for Silence Therapeutics?

The stock symbol for Silence Therapeutics is "SLN."

What Is the Silence Therapeutics Market Cap?

As of today, Silence Therapeutics market cap is 238.51M.

What Is Silence Therapeutics's Earnings Per Share (TTM)?

The Silence Therapeutics EPS (TTM) is -1.68.

When Is the Next Silence Therapeutics Earnings Date?

Silence Therapeutics will release its next earnings report on 17 Nov 2025.

From a Technical Analysis Perspective, Is SLN a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Strong Sell.

How Many Times Has Silence Therapeutics Stock Split?

Silence Therapeutics has split 0 times.

How Many Employees Does Silence Therapeutics Have?

Silence Therapeutics has 116 employees.

What is the current trading status of Silence Therapeutics (SLN)?

As of 08 Aug 2025, Silence Therapeutics (SLN) is trading at a price of 5.04, with a previous close of 5.38. The stock has fluctuated within a day range of 5.02 to 5.50, while its 52-week range spans from 1.97 to 20.48.

What Is Silence Therapeutics (SLN) Price Target According to Analysts?

The average 12-month price target for Silence Therapeutics is USD32.36714, with a high estimate of USD75 and a low estimate of USD3. 6 analysts recommend buying the stock, while 1 suggest selling, leading to an overall rating of Buy. The stock has an +542.21% Upside potential.
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