Merck stock price target cut to $115 at Guggenheim

Published 12/02/2025, 13:58
Merck stock price target cut to $115 at Guggenheim

On Wednesday, Guggenheim maintained a Buy rating on Merck (NYSE:MRK) shares but reduced the price target to $115 from $122. The adjustment follows a comprehensive review of the pharmaceutical giant’s fourth-quarter earnings and future outlook. Currently trading near its 52-week low of $85.73, InvestingPro analysis suggests the stock is undervalued, with technical indicators showing oversold conditions. Guggenheim hosted Merck’s management team for a webinar, which provided insights into the company’s recent performance and strategic plans.

During the webinar, Merck’s Chairman and CEO Robert Davis, CFO Caroline Litchfield, President of Merck Research Labs Dean Li, and Head of IR Peter Dannenbaum discussed the fourth-quarter results and elaborated on the company’s key products and strategic initiatives. With a robust gross profit margin of 80.85% and revenue growth of 6.74%, they highlighted Gardasil and Keytruda, two major products in Merck’s portfolio, and shed light on potential opportunities that might be undervalued by investors. InvestingPro subscribers can access detailed financial health scores and comprehensive analysis of Merck’s performance metrics.

Guggenheim’s decision to lower the price target was influenced by revised sales estimates for Gardasil, which were tempered due to recent data. However, this was partially balanced by increased confidence in Merck’s management, particularly regarding the conversion of patients to subcutaneous Keytruda, a leading cancer treatment.

The updated company model for Merck, which incorporates the fourth-quarter earnings and initial guidance for the fiscal year 2025, prompted Guggenheim to reiterate its Buy rating. The new discounted cash flow (DCF) derived price target reflects a nuanced view of Merck’s prospects, considering both the challenges and potential growth drivers.

The firm’s analysis indicates that while there are adjustments to be made in the near term, the long-term outlook for Merck remains positive, with strategic initiatives and pipeline developments expected to contribute to the company’s success. The company’s strong fundamentals are reflected in its P/E ratio of 12.89 and impressive 55-year history of maintaining dividend payments. For deeper insights into Merck’s valuation and growth prospects, InvestingPro offers exclusive access to advanced financial metrics and expert analysis.

In other recent news, Neuphoria Therapeutics has announced a $15 million milestone payment from Merck, marking the initiation of a Phase 2 clinical trial for MK-1167, aimed at treating Alzheimer’s disease symptoms. This payment is part of their collaborative research agreement, which could lead to Neuphoria receiving up to $450 million in additional milestone payments along with royalties on net sales of any licensed medicines.

On another note, Merck has also initiated a pivotal Phase 3 clinical trial for its investigational drug zilovertamab vedotin, aimed at treating patients with previously untreated diffuse large B-cell lymphoma. This move follows positive outcomes from the Phase 2 trial and aims to establish the benefits of the new combination regimen.

However, Merck’s stock has seen a series of price target revisions by multiple analyst firms recently. Bernstein SocGen Group lowered its price target to $95, citing concerns over Merck’s vaccine Gardasil. Similarly, TD Cowen downgraded Merck’s shares from "Buy" to "Hold" and reduced its price target to $100, citing unpredictability regarding Gardasil in the Chinese market. BMO Capital Markets followed suit, cutting its price target to $96 while maintaining a Market Perform rating, also due to shifts in expectations for Gardasil.

These are among the latest developments for both Neuphoria Therapeutics and Merck, as they continue to navigate the dynamic landscape of the biotech and pharmaceutical industries.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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