Canaccord lifts Verve Therapeutics stock target to $39

Published 15/04/2025, 12:26
Canaccord lifts Verve Therapeutics stock target to $39

Tuesday, Canaccord Genuity analysts raised their price target on Verve Therapeutics (NASDAQ:VERV) shares to $39.00, up from $39.00, while maintaining a Buy rating. The stock, which has seen a remarkable 38.72% gain over the past week, currently trades near $4.12. According to InvestingPro data, analyst price targets for VERV range from $15 to $39, suggesting significant potential upside from current levels. The adjustment follows Verve’s release of promising Phase 1b data for its candidate, VERVE-102. The clinical trial involved 14 patients across three dosage groups, with each patient monitored for at least 28 days. The results indicated no treatment-related serious adverse events (SAEs), no significant changes in liver enzymes (ALT) or platelet counts, and no increase in adverse event rates correlated with higher doses. With a market capitalization of $366 million and a strong financial position - InvestingPro analysis shows the company holds more cash than debt on its balance sheet - Verve appears well-positioned to advance its clinical programs.

Verve Therapeutics achieved its LDL-C (bad cholesterol) reduction target of 40-60%, with an average decrease of 53% among participants. The company’s success in meeting and surpassing its safety and efficacy goals led Canaccord Genuity to increase their probability of success (POS) for the VERVE-102 program from 50% to 70%.

Looking ahead, Verve Therapeutics is preparing to present an option package to Eli Lilly (not covered in the report) and is expecting a decision in the second half of 2025. Additionally, the company plans to release updated data, including results from higher doses, at a major medical meeting later this year.

The announcement of these advancements and the subsequent price target increase reflect confidence in the ongoing development and potential market impact of Verve’s cholesterol-lowering therapy. The positive data and the raised price target underscore Verve Therapeutics’ position in the biotechnology sector as it continues to progress through clinical trials and towards potential commercialization. Investors should note that the company’s next earnings report is scheduled for May 7, 2025. For deeper insights into VERV’s financial health, growth prospects, and detailed analysis, explore the comprehensive research available on InvestingPro, which offers exclusive access to over 30 key financial metrics and professional-grade analysis tools.

In other recent news, Verve Therapeutics announced promising results from its Heart-2 Phase 1b clinical trial for VERVE-102, a gene-editing therapy aimed at reducing LDL cholesterol levels. The trial demonstrated a favorable safety profile and significant LDL-C reductions, with the highest dose cohort showing an average LDL-C reduction of 53% and a peak reduction of 69%. Cantor Fitzgerald upgraded Verve’s stock rating to Overweight following these results, citing the absence of serious adverse events and a strong financial position with $524.3 million in cash and equivalents. Goldman Sachs also highlighted the efficacy of VERVE-102, noting a dose-dependent reduction in PCSK9 and LDL-C levels, supporting the continued development of the treatment. Jefferies reiterated a Buy rating with a $28 price target, emphasizing the stock’s upside potential and alignment with the company’s guidance. Verve Therapeutics plans to initiate a Phase 2 trial in the second half of 2025, with an opt-in decision from Eli Lilly and Company (NYSE:LLY) expected during the same period. The FDA has granted Fast Track designation for VERVE-102, potentially expediting its review process. Additionally, the company has discontinued the development of VERVE-101 but will continue long-term monitoring of its participants.

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