Cantor Fitzgerald maintains Overweight rating on Septerna stock with $50 target

Published 11/02/2025, 13:30
Cantor Fitzgerald maintains Overweight rating on Septerna stock with $50 target

On Tuesday, Cantor Fitzgerald reaffirmed its Overweight rating on Septerna Inc (NASDAQ:SEPN) with a price target of $50.00, representing significant upside from the current price of $13.17. The firm’s analysis suggests that the market for hypoPTH treatments can support several highly successful therapies, even with potential competition from MBX’s program. According to InvestingPro data, analyst targets for the stock range from $38 to $50, with a strong Buy consensus rating of 1.25. The positive outlook for Septerna is grounded in the anticipated peak sales for their lead product, SEP-786, which are projected to reach $820 million globally, along with an additional $250 million attributed to the company’s platform value. With a current market capitalization of $585 million and strong financial health indicators - including a current ratio of 10.08 and more cash than debt on its balance sheet - InvestingPro analysis suggests the stock is currently trading below its Fair Value.

Septerna Inc, which is actively developing treatments for hypoPTH, a condition characterized by an abnormally low level of parathyroid hormone, has been identified by Cantor Fitzgerald as a company with significant growth potential. The Overweight rating implies that analysts at Cantor Fitzgerald expect the stock to outperform the average return of the stocks in the analyst’s coverage universe over the next 12 to 18 months.

The reiterated price target of $50.00 per share reflects confidence in the company’s development pipeline and its commercial prospects. The evaluation by Cantor Fitzgerald takes into account the competitive landscape in the hypoPTH market, acknowledging the presence of other therapies while still highlighting the strong position of Septerna’s SEP-786.

Septerna’s focus on hypoPTH treatments is part of a broader strategy to address endocrine disorders with unmet medical needs. The company’s commitment to innovation and its strategic approach to navigating a competitive market are key factors underpinning the analyst’s continued endorsement.

Investors and market watchers will likely keep a close eye on Septerna’s progress, especially as it relates to the development and potential commercialization of SEP-786. The stock has faced challenges, declining 42.5% year-to-date, but maintains healthy fundamentals. The reaffirmation of the Overweight rating and $50.00 price target by Cantor Fitzgerald signals a steady confidence in the company’s prospects and may influence market sentiment towards Septerna’s stock. For deeper insights into Septerna’s financials and 8 additional key ProTips, visit InvestingPro.

In other recent news, Septerna, a biotechnology firm, has announced the appointment of Gil Labrucherie as its new Chief Financial Officer. Labrucherie, with over two decades of experience in senior finance and legal roles within the biopharmaceutical sector, is expected to contribute significantly to Septerna’s growth and the advancement of its product pipeline. Additionally, Cantor Fitzgerald initiated coverage on Septerna, assigning the firm an Overweight rating based on the company’s growth prospects, particularly in the G protein-coupled receptors (GPCR) field.

In other developments, TD Cowen initiated coverage on Septerna with a Buy rating, expressing optimism based on preclinical data from Septerna’s leading drug candidate, SEP-786. The firm anticipates Phase 1 data for SEP-786 in mid-2025 and an Investigational New Drug (IND) application for another drug candidate, SEP-631, to be filed in 2025. Moreover, JPMorgan initiated coverage on Septerna with an Overweight rating, highlighting the company’s innovative approach within the biopharmaceutical industry, particularly its Native Complex Platform.

All these recent developments underscore the confidence of various analysts in Septerna’s strategic focus on GPCR drug development and its ability to deliver value to its investors.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

Latest comments

Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers
© 2007-2025 - Fusion Media Limited. All Rights Reserved.