Cantor Fitzgerald reiterates Overweight rating on aTyr Pharma stock

Published 12/09/2025, 12:26
Cantor Fitzgerald reiterates Overweight rating on aTyr Pharma stock

Investing.com - Cantor Fitzgerald has reiterated an Overweight rating on aTyr Pharma (NASDAQ:ATYR) stock, maintaining its positive outlook on the biopharmaceutical company. The stock has shown strong momentum with a 48% gain over the past six months, though InvestingPro analysis indicates the stock is currently trading above its Fair Value.

The firm’s analysis focuses on aTyr Pharma’s ongoing clinical trial, which has a primary endpoint measuring absolute steroid reduction versus placebo at Week 48, using a trailing 4-week average compared to baseline. With a current ratio of 5.63 and more cash than debt on its balance sheet, the company appears well-positioned to fund its clinical development programs.

According to Cantor Fitzgerald, aTyr’s management has indicated the trial is well-powered to demonstrate a 3 mg/day delta compared to placebo on the primary endpoint.

The research note states that patient discontinuation in the trial is estimated at 10% or less, based on management comments.

Cantor Fitzgerald estimates the trial has strong statistical power (greater than 80%) to show even a lower approximately 2.5 mg/day steroid reduction improvement versus placebo on the primary endpoint.

In other recent news, aTyr Pharma has been the focus of several analyst updates as it approaches a significant milestone. The company recently completed its pivotal Phase 3 EFZO-FIT study for efzofitimod, a treatment for pulmonary sarcoidosis. H.C. Wainwright has reiterated its Buy rating with a $35.00 price target following this development. Jefferies also raised its price target on aTyr Pharma to $17.00 from $9.00, maintaining a Buy rating in anticipation of the trial results. Cantor Fitzgerald has reiterated an Overweight rating after discussions with management, emphasizing the importance of the upcoming Phase 3 trial data. Similarly, Leerink Partners maintained an Outperform rating with a $16.00 price target, noting management’s optimism about the trial’s outcome. The trial results are expected to be released in early-to-mid September, with further details to be presented at the European Respiratory Society conference. These developments highlight the anticipation surrounding aTyr Pharma’s lead drug candidate as it nears a critical juncture.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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