Jefferies downgrades Opko Health stock to Hold on flat Ngenla sales

Published 30/10/2025, 21:54
Jefferies downgrades Opko Health stock to Hold on flat Ngenla sales

Investing.com - Jefferies downgraded Opko Health (NASDAQ:OPK) from Buy to Hold on Thursday, while lowering its price target to $1.60 from $2.00.

The downgrade comes as Jefferies expressed concerns about flat year-over-year guidance of $32-35 million for Ngenla, Opko’s growth hormone product developed with Pfizer, for 2026.

Jefferies noted that Ngenla sales have remained flat for seven consecutive quarters since its launch, prompting the firm to reduce its estimates for the product’s future performance.

While acknowledging potential in Opko’s drug pipeline, Jefferies characterized these programs as still early-stage with unclear catalysts, making growth challenging under the current business structure.

The firm maintained that Opko remains interesting from a sum-of-parts valuation perspective, with potential upside if the company sells the remainder of its diagnostics business.

In other recent news, Opko Health Inc. reported its financial results for the third quarter of 2025, showcasing a stronger-than-expected performance. The company achieved a net income of $21.6 million, or $0.03 per share, surpassing analysts’ expectations of a loss of $0.06 per share. However, the company’s revenue was $151.6 million, which fell short of the anticipated $160.78 million. These results indicate a mixed performance, with earnings exceeding projections but revenue slightly underperforming. There were no significant mergers or acquisitions announced in conjunction with these earnings. Additionally, there has been no recent analyst upgrade or downgrade reported for Opko Health. These developments provide investors with a clearer view of the company’s current financial standing.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

Latest comments

Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers
© 2007-2025 - Fusion Media Limited. All Rights Reserved.