Stifel maintains Buy rating and $155 target on Blueprint Medicines stock

Published 07/01/2025, 19:46
Stifel maintains Buy rating and $155 target on Blueprint Medicines stock

On Tuesday, Stifel analysts reiterated their Buy rating for Blueprint Medicines (NASDAQ:BPMC) with a price target of $155.00. According to InvestingPro data, the stock has analyst targets ranging from $81 to $167, with 4 analysts recently revising their earnings expectations upward.

The endorsement comes with an optimistic outlook on the company's development strategy, particularly for its BLU-808 drug. Blueprint Medicines has been recognized for its strategic approach, which emphasizes the importance of managing on-target toxicity and defining the right dosing strategy to benefit a diverse range of patients with mast cell-driven diseases.

The analysts highlighted the potential of BLU-808, an oral drug, to match the potency of wtKIT antibodies and offer unique dosing regimens that could improve patient adherence and chronic treatment management. According to the analysts, Phase 1 data should support the company's approach, which is distinct from competitors who might rush towards seeking high-dose approvals.

Blueprint Medicines' financial position is also seen as a strong point, with Stifel noting the company's capability to pursue a disciplined development strategy. InvestingPro analysis shows the company maintains a healthy current ratio of 3.32, with liquid assets exceeding short-term obligations. This strategy allows the exploration of various use cases while maintaining a sustainable balance sheet and cash flow. In contrast, other biotech firms working on wtKIT treatments may face higher capital demands.

The analysts expressed confidence that Blueprint Medicines' shares have the potential to reach all-time highs, especially if the year 2025 demonstrates the sustained growth of Ayvakit with a peak sales visibility of more than $2 billion. Additionally, the initial clinical data for BLU-808 is anticipated to bolster the company's inflammation and immunology (I&I) pipeline narrative with a development thesis that sets it apart from others in the field.

In other recent news, Blueprint Medicines reported significant revenue growth, primarily driven by robust sales of its therapeutic product, Ayvakit, used for treating systemic mastocytosis. Ayvakit generated $128.2 million in net product revenue, marking a 137% year-over-year increase, leading the company to adjust its revenue expectations for the year to between $475 million and $480 million. JPMorgan initiated coverage on Blueprint Medicines with an Overweight rating and set a price target of $126.00, while Needham maintained a Buy rating and increased the price target to $135 from $133.

Both firms highlighted the potential for sustained growth driven by Ayvakit sales, with JPMorgan estimating a peak sales figure of $2.9 billion. Blueprint Medicines is also preparing to release data from the BLU808 Single Ascending Dose/Multiple Ascending Dose study next year, and plans to initiate the registration-enabling study for Elenestinib by the end of 2024.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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