Wells Fargo initiates Soleno Therapeutics stock with Overweight rating

Published 20/08/2025, 11:20
Wells Fargo initiates Soleno Therapeutics stock with Overweight rating

Investing.com - Wells Fargo (NYSE:WFC) initiated coverage on Soleno Therapeutics Inc. (NASDAQ:SLNO), a $3.6 billion market cap biotech company, with an Overweight rating and a price target of $123.00 on Wednesday. According to InvestingPro data, analysts maintain a Strong Buy consensus with price targets ranging from $106 to $145.

The research firm’s decision comes as Soleno shares have declined 23% month-to-date, underperforming the SPDR S&P Biotech ETF’s 3% gain during the same period.

Wells Fargo attributes the recent stock weakness to concerns about the safety of Soleno’s VYKAT treatment, competitive pressures, and the company’s recent financing that may suggest mergers and acquisitions are not imminent.

The firm considers these concerns "overblown" and expresses confidence in VYKAT’s potential in the Prader-Willi syndrome (PWS) market, citing significant unmet medical needs and enthusiasm for treatment options.

Wells Fargo recommends buying Soleno stock at current levels, predicting steady share price appreciation over the next 12 months as VYKAT gains market traction.

In other recent news, Soleno Therapeutics reported $32.7 million in revenue for the second quarter, marking a strong start for its Vykat launch. This was highlighted by Stifel, which increased its price target for Soleno to $118, citing encouraging demand and prescriber engagement. TD Cowen also reiterated its Buy rating and $120 price target, noting strong sales momentum with 646 patient start forms. Meanwhile, H.C. Wainwright raised its price target from $100 to $110, maintaining a Buy rating despite a Citizen Petition from Scorpion Capital calling for VYKAT XR’s withdrawal. Cantor Fitzgerald and Baird both maintained positive ratings, with price targets of $123 and $121, respectively. Cantor Fitzgerald emphasized Soleno’s ongoing education efforts with healthcare providers. However, Baird’s reiteration followed a short report alleging safety concerns with Soleno’s drug, Vykat. These developments reflect a mix of confidence and scrutiny in Soleno’s market activities.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

Latest comments

Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers
© 2007-2025 - Fusion Media Limited. All Rights Reserved.