William Blair initiates coverage on Kyverna Therapeutics stock with Outperform rating

Published 20/08/2025, 10:54
William Blair initiates coverage on Kyverna Therapeutics stock with Outperform rating

Investing.com - William Blair initiated coverage on Kyverna Therapeutics Inc (NASDAQ:KYTX), currently valued at $152 million, with an Outperform rating and set a $27 fair-value estimate. The stock currently trades significantly below analyst targets, which range from $5 to $25.

The research firm identified Kyverna as a clinical-stage biotechnology company focused on developing immune cell therapies for severe autoimmune diseases that aim to induce long-term remissions without requiring chronic immunosuppression. According to InvestingPro data, the company maintains a strong financial position with more cash than debt and liquid assets exceeding short-term obligations.

William Blair highlighted KYV-101, the company’s lead candidate, as an autologous CD19 CAR-T therapy that has been evaluated in over 40 patients across 15 autoimmune indications, with patient follow-up extending beyond two years.

The firm expressed confidence that Kyverna is positioned to secure the first FDA approval for a CAR-T therapy treating an autoimmune disease, potentially establishing the company as a leader in this therapeutic area.

William Blair suggested this potential milestone could enable Kyverna to rapidly advance additional indications for its therapies.

In other recent news, Kyverna Therapeutics has announced the appointment of Marc Grasso as its new Chief Financial Officer. Dr. Grasso takes over from Ryan Jones, who will be moving to a strategic advisor role within the company. With over 25 years of experience in public company operations, capital markets, and investment banking, Dr. Grasso’s expertise is expected to be a valuable asset to Kyverna Therapeutics. This leadership change comes at a crucial time as the company continues its focus on developing cell therapies for autoimmune diseases. The transition is part of Kyverna’s ongoing strategy to strengthen its executive team. While no specific financial results or projections were announced alongside this appointment, the move signals a potential shift in the company’s financial strategy. Investors and stakeholders may be keen to see how Dr. Grasso’s appointment impacts Kyverna’s future financial planning and operations.

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