Arrowhead Pharmaceuticals stock falls after Sarepta sells shares

Published 14/08/2025, 14:16
© Reuters.

Investing.com -- Arrowhead Pharmaceuticals Inc (NASDAQ:ARWR) stock dropped 6% after Sarepta Therapeutics (NASDAQ:SRPT) announced it sold over 9.2 million shares of Arrowhead in a privately negotiated block trade.

Sarepta expects to receive at least $174 million in gross proceeds from the transaction. Additionally, Sarepta will transfer approximately 2.66 million Arrowhead shares to satisfy $50 million of a previously announced $100 million milestone payment obligation.

The milestone payment was triggered following safety data review and Arrowhead achieving the first of two predetermined enrollment targets in the Phase 1/2 clinical study of SRP-1003, an investigational RNA interference therapeutic for type 1 myotonic dystrophy (DM1).

Despite selling its equity stake, Sarepta CEO Doug Ingram emphasized that the decision was strategic to help fund the milestone payment and does not reflect any change in the company’s confidence in the siRNA approach or Arrowhead’s technology.

Sarepta plans to release preliminary data from its FSHD and DM1 programs in the second half of this year, with more comprehensive data from the Phase 1/2 study of SRP-1003 expected in the second half of 2025.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

Latest comments

Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers
© 2007-2025 - Fusion Media Limited. All Rights Reserved.