Citi raises Zymeworks stock price target to $19, maintains Buy

Published 06/03/2025, 12:56
Citi raises Zymeworks stock price target to $19, maintains Buy

On Thursday, Citi analyst increased the price target for Zymeworks shares, listed on (NASDAQ:ZYME), to $19 from the previous target of $18, while reaffirming a Buy rating for the company’s stock. Currently trading at $13.18, the stock sits below analyst targets ranging from $12 to $30. According to InvestingPro data, the company maintains a "GOOD" overall financial health score, suggesting solid fundamentals despite development-stage status.

The adjustment comes after an evaluation of Zymeworks’ strategic financial decisions, particularly regarding its early clinical development expenditures. The company’s recently appointed CFO/CBO is credited with advocating for a more disciplined budget approach, leading to the deprioritization of ZW220 (NaPi2b ADC), an antibody-drug conjugate in their pipeline. This financial discipline is reflected in the company’s strong balance sheet, with InvestingPro analysis showing more cash than debt and a healthy current ratio of 3.4x.

Citi’s analysis suggests that the decision to shift focus away from ZW220 demonstrates a notable fiscal discipline, as there were no fundamental issues with the drug that would have necessitated a reallocation of resources. The analyst believes that this strategic choice does not preclude the possibility of ZW220 being revisited in the future, either through internal development efforts or via a partnership.

The firm’s commentary highlights that, among Zymeworks’ various pipeline projects, the investment in the GPC3-targeting ZW251 and the emerging autoimmune program are seen as more promising ventures that could potentially yield higher returns on research and development capital.

In summary, Citi maintains a positive outlook on Zymeworks and supports the company’s strategic prioritization of projects within its pipeline, which is reflected in the increased price target and the continued Buy rating. While the company reported revenue of $76.3M in the last twelve months, InvestingPro analysis indicates it’s not yet profitable, though this is typical for clinical-stage biotech companies. Discover more insights and 12+ additional ProTips about Zymeworks with an InvestingPro subscription, including detailed analysis in the comprehensive Pro Research Report.

In other recent news, Zymeworks Inc . reported a net loss of $122.7 million for fiscal year 2024, with a modest revenue increase to $76.3 million from the previous year’s $76.0 million. The company highlighted its strong cash position, which is expected to sustain operations into the second half of 2027. Additionally, the launch of Zanodetimab by Jazz Pharmaceuticals (NASDAQ:JAZZ) is seen as a potential revenue booster. Zymeworks also achieved a $14 million research milestone from GSK, reflecting ongoing value from its partnerships. Analysts have noted the company’s focus on advancing its therapeutic pipeline, with plans to submit an Investigational New Drug (IND) application for ZW251 in mid-2025. The company continues to emphasize its strategic collaborations, which include partnerships with industry leaders such as Bristol Myers (NYSE:BMY) Squibb and BeiGene (NASDAQ:ONC). Despite the challenges of marginal revenue growth and ongoing net losses, Zymeworks remains committed to advancing its next generation of therapeutics.

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