Mizuho sets $55 target on Guardant Health stock, cites growth potential

Published 09/04/2025, 22:10
Mizuho sets $55 target on Guardant Health stock, cites growth potential

On Wednesday, Mizuho (NYSE:MFG) Securities initiated coverage on Guardant Health (NASDAQ:GH) shares with an Outperform rating and set a price target of $55.00, representing a 25% upside from the current price of $43.87. The precision oncology company, currently valued at $5.4 billion, is recognized for its innovative suite of products aimed at transforming cancer treatment and monitoring. According to InvestingPro data, the stock has delivered impressive returns, gaining over 107% in the past year.

Guardant Health's technology, particularly its Smart Liquid Biopsy platform, stands out from tissue-based competitors, offering a significant advantage in the market. The company has demonstrated strong execution with 31% revenue growth in the last twelve months and maintains a robust 61% gross profit margin. Mizuho analysts highlight the company's immediate access to an almost $20 billion total addressable market (TAM) for Precision Oncology, spanning colorectal, breast, and lung cancer indications.

The firm's positive outlook is further supported by the strong survey responses for Guardant's blood-based colorectal cancer (CRC) test. InvestingPro analysis shows the company maintains a "GOOD" overall financial health score, despite current negative EBITDA. Analysts anticipate that the company's cash flow and profitability will benefit from the successful adoption of its products.

The $55 price target set by Mizuho suggests a valuation of approximately 7.5 times the company's expected enterprise value to sales ratio for the fiscal years 2025 and 2026. This valuation is higher than that of its small to mid-size (SMID) industry peers, but Mizuho justifies this premium with Guardant Health's impending sales growth and profit potential. The strong analyst consensus, with targets ranging from $47 to $65, supports this optimistic outlook. Get deeper insights and access to comprehensive financial analysis through InvestingPro's exclusive research reports.

In other recent news, Guardant Health has announced that its Shield blood test for colorectal cancer is now covered by the U.S. Department of Veterans Affairs (VA) for eligible veterans. This coverage is significant as it extends to veterans receiving community care authorized by the VA and includes no copay for average-risk individuals aged 45 and older. Additionally, Guardant Health has partnered with Bayshore HealthCare to offer its cancer diagnostic tests in Canada, enhancing access to advanced screening tools for over 350,000 patients annually. In a strategic operational move, Guardant Health has secured a lease extension for its facilities in Redwood (NYSE:RWT) City, California, through 2031. This extension, valued at approximately $50 million, aligns with the company's financial strategy and operational needs.

TD Cowen has maintained a Buy rating on Guardant Health, with a target price of $56, following the approval of the Shield test as an Advanced Diagnostic Laboratory Test (ADLT). This approval allows for a higher billing rate under Medicare, potentially increasing revenue estimates by 2.5-3% in 2025. The ADLT status is expected to positively impact Guardant Health's financial performance, with a boost in gross margins and a reduction in the burn rate. These developments reflect Guardant Health's ongoing efforts to expand the reach and financial viability of its cancer screening solutions.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

Latest comments

Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers
© 2007-2025 - Fusion Media Limited. All Rights Reserved.