Oppenheimer maintains $13 target on Nyxoah shares post-FDA talks

Published 31/03/2025, 12:22
Oppenheimer maintains $13 target on Nyxoah shares post-FDA talks

On Monday, Oppenheimer reaffirmed its Outperform rating and $13.00 price target on Nyxoah SA (NASDAQ:NYXH) shares, despite the stock’s significant 32.3% decline over the past week. According to InvestingPro data, the company is currently trading near its 52-week low of $6.76, suggesting potential value opportunity based on InvestingPro’s Fair Value analysis. The firm’s analysts held discussions with Nyxoah’s management last Friday to address questions regarding the FDA’s Approvable Letter for the company’s Genio PMA application. The central issue relates to the FDA’s requirements for Nyxoah’s manufacturing process.

According to the analysts, Nyxoah believed that only a verification of its manufacturing process was necessary, as it utilized standard materials and processes. However, the FDA has indicated that it wants Nyxoah to validate its materials and processes with new data. This discrepancy has been the subject of multiple discussions between Nyxoah and the FDA since last Wednesday, as they work to determine whether verification or validation is the appropriate course of action. The company maintains a strong liquidity position with a current ratio of 4.56 and more cash than debt on its balance sheet, potentially providing flexibility during this regulatory process.

If validation is deemed necessary by the FDA, Nyxoah will need to identify what data must be produced to meet the FDA’s requirements. The outcome of these discussions could have significant implications for the company’s ability to bring its Genio system to market in the United States.

Nyxoah’s Genio system is a product designed to treat obstructive sleep apnea, a condition that affects millions of people worldwide. The system’s approval process is being closely monitored by investors and industry observers, as it represents a potentially significant advancement in the treatment of this common sleep disorder.

The ongoing negotiations with the FDA will determine the next steps for Nyxoah in its quest to secure approval for the Genio system. The company’s management and the regulatory agency are continuing their dialogue in an effort to resolve the outstanding issues surrounding the PMA application. For investors seeking deeper insights, InvestingPro offers comprehensive analysis with 12 additional ProTips and a detailed Pro Research Report, providing valuable context about Nyxoah’s financial health, market position, and growth prospects.

In other recent news, Nyxoah’s Genio system, designed for obstructive sleep apnea, is under close scrutiny as investors await potential FDA approval. The company received an "Approvable Letter" from the FDA, indicating that while approval is close, certain conditions must still be met. Analysts at Stifel have maintained a Buy rating for Nyxoah, adjusting their price target to $15, with expectations that FDA approval could significantly impact the stock. H.C. Wainwright also maintains a Buy rating, with a $17 target, highlighting Nyxoah’s fourth-quarter sales of €1.3 million, which, when adjusted for deferred revenues, showed a 46% quarter-over-quarter increase. Despite recent quarterly revenue figures falling below expectations, Nyxoah’s gross margins have been better than anticipated. The company is actively preparing for the potential U.S. launch of Genio, having trained over 75 physicians and assembled a sales team, with plans to expand further by 2025. Nyxoah’s international expansion continues with recent launches in the UK and the Middle East, and the company aims to penetrate these markets further. Stifel anticipates U.S. Genio sales could reach $10 million in the latter half of 2025, with market share growth projected in the following years.

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