Stifel maintains Soleno Therapeutics buy rating post FDA nod

Published 27/03/2025, 13:46
Stifel maintains Soleno Therapeutics buy rating post FDA nod

On Thursday, Stifel analysts maintained a Buy rating on Soleno Therapeutics Inc. (NASDAQ:SLNO) shares, with a steady price target of $74.00. Currently trading at $48.97, the stock shows significant upside potential according to InvestingPro data, with analyst targets ranging from $70 to $123. The endorsement comes on the heels of the U.S. Food and Drug Administration’s approval of Soleno’s VYKAT XR (DCCR) for the treatment of Prader-Willi Syndrome (PWS), a genetic disorder characterized by a constant sense of hunger, among other symptoms.

The analysts at Stifel expressed optimism about the drug’s market launch, citing the FDA’s favorable labeling and the drug’s pricing, which exceeded their expectations at approximately $466,000 on average. They believe VYKAT XR is well-positioned for a strong market entry, given the significant unmet need in PWS treatment, a well-diagnosed and concentrated patient population, a favorable risk/benefit profile, and high awareness among physicians and patients. With a market capitalization of $2.25 billion and strong financial health indicators, including a current ratio of 15.68, the company appears well-positioned to support the launch.

Stifel’s analysis suggests that VYKAT XR stands apart from recent rare disease drug launches, which may have started strong but showed signs of plateauing. They argue that VYKAT XR’s unique characteristics differentiate it from these other drugs, potentially leading to a different trajectory in terms of market uptake and sustained performance.

The firm anticipates that Soleno Therapeutics’ stock will experience a meaningful increase following the FDA’s approval and continue to rise over time. They attribute this projection to investor interest in launches within challenging market conditions and the potential for mergers and acquisitions, which could provide additional upside for the stock.

Soleno Therapeutics’ recent success with VYKAT XR is expected to draw significant investor attention, as the approval marks a milestone in the company’s efforts to address the needs of patients with PWS. With analysts projecting profitability this year and net income growth, the company’s financial outlook appears promising. Stifel’s continued endorsement reflects confidence in the drug’s commercial potential and the overall direction of the company. Access comprehensive analysis and valuation metrics through the detailed Pro Research Report available on InvestingPro.

In other recent news, Soleno Therapeutics has made significant strides with the FDA approval of its Vykat XR for treating hyperphagia in Prader-Willi syndrome. This approval has led to a series of analyst upgrades and increased price targets. Oppenheimer raised its price target to $105, emphasizing the drug’s potential to generate peak sales of $2 billion in the U.S. Cantor Fitzgerald also nearly doubled its target to $123, citing strong market demand and the drug’s supportive pricing. Baird followed suit, setting a new target of $102, highlighting the approval as a critical catalyst for Soleno’s valuation. Stifel maintained its Buy rating with a $74 target, expressing optimism about Vykat XR’s market potential and its favorable pricing. Analysts agree that the FDA approval marks a pivotal moment for Soleno, with expectations for robust commercial success and potential growth opportunities. The consensus is that the drug’s clean label and strategic positioning will likely drive significant market impact. These developments have positioned Soleno as a company to watch, with analysts expressing confidence in its future trajectory.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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