TD Cowen holds Vertex stock Buy rating, $525 price target

Published 11/02/2025, 15:24
TD Cowen holds Vertex stock Buy rating, $525 price target

On Tuesday, TD Cowen reaffirmed its confidence in Vertex Pharmaceuticals (NASDAQ:VRTX), maintaining a Buy rating and a $525.00 price target. The firm has highlighted Vertex as its top large-cap (L.C.) biotech pick for the year 2025. Currently trading at $469.97 with a market capitalization of $121 billion, InvestingPro analysis suggests the stock is slightly overvalued relative to its Fair Value, though it maintains strong momentum with a 16.7% return year-to-date. Following a strong fourth-quarter performance, with cystic fibrosis (CF) revenues reaching $2.9 billion, surpassing the consensus estimate of $2.77 billion, Vertex’s stock has garnered positive attention. Despite non-GAAP earnings per share (EPS) falling slightly short at $3.98 compared to the expected $4.00, the company’s outlook remains robust. InvestingPro data shows the company maintains healthy financials with a strong current ratio of 2.47 and operates with moderate debt levels. Subscribers can access 8 additional ProTips and comprehensive financial metrics through the Pro Research Report.

Vertex provided a full-year 2025 revenue guidance ranging between $11.75 billion and $12 billion, indicating an 8% year-over-year growth at the midpoint, which is slightly below the consensus forecast of $11.84 billion. The anticipated growth factors in a moderation of CF revenue growth, which is expected to be balanced by revenue from new product launches. One of the key drivers for future revenue is Journavx, set to be available by the end of February, with significant revenue contributions projected for the second half of 2025.

TD Cowen’s price target of $525 for Vertex is underpinned by a discounted cash flow (DCF) analysis. The firm projects that Vertex’s CF revenue will increase from $11.01 billion in 2024 to $15.1 billion by 2030. This forecast is supported by the company’s maturing pipeline, which includes three ongoing product launches and four programs in pivotal trials. According to TD Cowen, these developments will enable Vertex to achieve a compound annual growth rate (CAGR) of 9% in revenue through 2030.

The endorsement of Vertex as a top large-cap biotech pick for 2025 underscores the firm’s belief in the company’s long-term growth prospects. TD Cowen’s analysis suggests that with the upcoming product launches and the strength of Vertex’s pipeline, the company is well-positioned for sustained growth in the coming years. With analyst targets ranging from $330 to $615 and impressive revenue growth of 10.06% in the last twelve months, InvestingPro subscribers can access detailed analysis and valuation metrics to make informed investment decisions.

In other recent news, Vertex Pharmaceuticals Incorporated has seen a flurry of activity from financial analysts. Truist Securities raised their price target for Vertex to $520, following positive feedback on the launches of Vertex’s drugs Alyftrek and Journavx. BMO Capital Markets also maintained its Outperform rating and $545 price target on Vertex, emphasizing the company’s growth potential and portfolio diversification.

Meanwhile, Morgan Stanley (NYSE:MS) adjusted its outlook on Vertex, raising the price target from $450 to $459, after the company reported a stronger-than-expected performance for the fourth quarter. Scotiabank (TSX:BNS) analyst Greg Harrison updated the price target for Vertex to $450, reflecting the company’s strong fourth-quarter performance. Lastly, Piper Sandler maintained an Overweight rating and a $533 price target on Vertex’s stock, following the company’s impressive quarterly revenue results and a solid initial financial outlook for 2025.

These recent developments underscore the positive outlook held by various analysts, with a particular focus on Vertex’s drug portfolio, strategic positioning, and financial performance. The company’s launch of new treatments Journavx and Alyftrek, coupled with its robust guidance for 2025, has drawn attention from stakeholders across the investment community.

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