Vertex stock price target raised to $520 at Truist Securities

Published 11/02/2025, 14:54
Vertex stock price target raised to $520 at Truist Securities

On Tuesday, Truist Securities increased the price target for Vertex Pharmaceuticals (NASDAQ:VRTX) Incorporated (NASDAQ: VRTX), a $121 billion biotechnology leader, from the previous $460.00 to a new target of $520.00. The firm maintained its Buy rating on the stock. The adjustment follows positive feedback on the launches of Vertex’s drugs Alyftrek and Journavx. According to InvestingPro data, analyst targets for Vertex now range from $330 to $615, reflecting diverse market expectations for this prominent industry player.

Joon Lee of Truist Securities expressed optimism about the market reception for Journavx, highlighting its potential as an alternative to opioids. According to Lee, the broad support for Journavx, even among political adversaries, is a testament to its unique positioning in the market. The analyst’s checks with doctors reaffirm this sentiment, suggesting a strong demand for the drug. This positive outlook aligns with Vertex’s solid revenue growth of 10% over the last twelve months.

Additionally, Lee noted that Alyftrek’s profile in treating cystic fibrosis (CF) is expected to facilitate a smooth launch. As Vertex’s fifth CF drug launch, the company has a track record that alleviates many concerns. However, Lee mentioned that Vertex should keep an eye on Sionna, a new player in the CF market, although Sionna currently has no rating (NR). InvestingPro analysis shows Vertex maintains a GOOD financial health score, with liquid assets exceeding short-term obligations and moderate debt levels. Subscribers can access 8 additional ProTips and comprehensive financial metrics in the Pro Research Report.

The report also pointed to other factors that could influence Vertex’s performance in 2025, including quarterly metrics for Casgevy and updates on the end-of-phase-two (EOP2) study for LSR. The raised price target reflects Vertex’s improved commercial outlook, as seen by Truist Securities.

The price target increase by Truist Securities indicates confidence in Vertex’s drug portfolio and strategic positioning within the pharmaceutical industry. Vertex’s stock may respond to these developments as the company continues to navigate the competitive landscape and regulatory milestones in the coming year.

In other recent news, Vertex Pharmaceuticals Incorporated has been the focus of several financial firms. BMO Capital Markets maintained its Outperform rating on Vertex, emphasizing the company’s growth potential and portfolio diversification through 2025. This followed Vertex’s recent financial results, which included a revenue guidance of $11.75 to $12.0 billion for 2025, largely driven by the launches of Alyftrek for cystic fibrosis and Journavx for acute pain management.

Simultaneously, Morgan Stanley (NYSE:MS) raised its price target for Vertex from $450.00 to $459.00, maintaining an Equalweight rating. This adjustment was in response to Vertex’s recent financial performance and guidance update. Scotiabank (TSX:BNS) also raised its price target for Vertex to $450, up from the previous $433, while maintaining a Sector Perform rating.

Piper Sandler maintained an Overweight rating and a $533.00 price target for Vertex, citing the company’s impressive quarterly revenue results and a solid initial financial outlook for 2025. Cantor Fitzgerald also reaffirmed its Overweight rating on Vertex with a consistent price target of $480.00, focusing on the potential effects of its medication Alyftrek on the company’s margins and earnings per share.

These recent developments reflect the financial community’s positive outlook on Vertex’s future growth, portfolio diversification, and financial performance.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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