William Blair initiates Insmed stock with Outperform rating

Published 20/08/2025, 07:04
William Blair initiates Insmed stock with Outperform rating

Investing.com - William Blair initiated coverage on Insmed (NASDAQ:INSM) with an Outperform rating on Wednesday. According to InvestingPro data, the company currently trades near its 52-week high of $130.13, with a market capitalization of $26.87 billion.

The firm cited potential for significant valuation increases driven by clinical and commercial execution with the company’s key products Brinsupri, Arikayce, and TPIP. The company’s strong commercial potential is supported by its impressive 21.15% revenue growth and healthy gross profit margin of 75.72%.

William Blair acknowledged Insmed shares have already risen over 450% since positive Phase III results for Brinsupri in bronchiectasis, compared to just a 2% increase for the XBI index during the same period.

The investment firm believes Brinsupri’s potential for a strong commercial launch in the multi-blockbuster bronchiectasis indication makes Insmed a "must-own name for investors."

William Blair also highlighted upcoming readouts that could expand market opportunities across all three products, potentially increasing Insmed’s peak sales to nearly $15 billion by 2035.

In other recent news, Insmed has received significant attention following the FDA approval of its drug Brinsupri (brensocatib), which has led to multiple analysts raising their stock price targets. H.C. Wainwright notably doubled its price target for Insmed to $240, highlighting the drug’s approval as a key catalyst for the company. Similarly, Wolfe Research increased its price target to $173, pointing to the upcoming chronic rhinosinusitis without nasal polyps readout as a potential catalyst. Stifel also raised its target to $145, emphasizing the significance of Brinsupri’s approval as the first therapy for non-CF bronchiectasis. TD Cowen followed suit with a new target of $154, noting the approval’s clean label without market-limiting warnings. Truist Securities raised its price target to $139, citing the broad label approval of Brinsupri as supportive of a multi-billion dollar opportunity. These developments reflect widespread optimism among analysts regarding Insmed’s future prospects.

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