Protagonist Therapeutics stock reaches all-time high at 73.34 USD

Published 10/10/2025, 18:42
Protagonist Therapeutics stock reaches all-time high at 73.34 USD

Protagonist Therapeutics Inc. stock reached an all-time high of 73.34 USD, marking a significant milestone for the $5.56 billion biopharmaceutical company. Over the past year, the stock has experienced a remarkable increase of 97.83%, with particularly strong momentum showing a 64% gain in the last six months. According to InvestingPro analysis, the stock appears overvalued at current levels, trading at a P/E ratio of 112. This surge highlights Protagonist Therapeutics’ successful advancement in its clinical pipeline and strategic partnerships, which have contributed to its robust market performance. The company’s focus on developing peptide-based therapeutics continues to attract attention, positioning it as a promising player in the biotech industry. With a beta of 2.2, investors should note the stock’s higher volatility compared to the market. For deeper insights into Protagonist’s financial health and growth prospects, access the comprehensive Pro Research Report available on InvestingPro.

In other recent news, Protagonist Therapeutics has been the focus of several analyst actions following the release of comprehensive data from their Phase 2b Anthem-UC trial. The trial data, which showed significant clinical response rates for all doses tested, prompted Clear Street to raise its price target for the company to $74 while maintaining a Buy rating. Similarly, BMO Capital reiterated its Outperform rating with a price target of $72, citing confidence in the results presented at Berlin’s UEG Conference. Barclays initiated coverage of Protagonist Therapeutics with an Overweight rating and a $72 price target, highlighting the company’s peptide technology platform as a positive factor. JMP Securities also increased its price target from $67 to $69, maintaining a Market Outperform rating. JMP expressed high confidence in the upcoming new drug application for rusfertide, assigning a 90% probability of approval next year. These developments reflect a generally positive sentiment among analysts regarding Protagonist Therapeutics’ recent achievements and future prospects.

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