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Silence Therapeutics PLC (SLN) stock has reached a 52-week low, touching down at $4.04, representing a stark 77% decline over the past six months. According to InvestingPro data, the biotechnology firm faces a tumultuous period marked by investor concerns and market headwinds, with analysts anticipating sales declines in the current year. This latest price level reflects a significant downturn from previous valuations, with the company’s shares experiencing a precipitous 1-year change of -83.4%. While the company maintains a strong liquidity position with a current ratio of 11.14 and more cash than debt on its balance sheet, the stark decline underscores the volatility and challenges within the biotech sector. Silence Therapeutics grapples with the pressures of clinical trial outcomes, regulatory hurdles, and broader economic factors influencing investor sentiment. For deeper insights into SLN’s financial health and growth prospects, including 8 additional ProTips, explore the comprehensive analysis available on InvestingPro.
In other recent news, Silence Therapeutics reported significant developments in its financial and strategic operations. The company announced a revenue increase to $43.3 million in 2024, up from $31.6 million in 2023, primarily driven by strategic collaborations with AstraZeneca (NASDAQ:AZN) and Hanseo Pharma. Analysts at H.C. Wainwright maintained a Buy rating with a $75 price target, highlighting Silence Therapeutics’ decision to delay the Phase 3 cardiovascular trial for zerlasiran until a partnership is secured as a prudent financial move. Meanwhile, Morgan Stanley (NYSE:MS) adjusted its price target to $45, citing updates to the company’s financial model and a reduced probability of success for zerlasiran. Jefferies also revised its price target to $30, noting the company’s strategic focus on its drug candidate divesiran, which aims to treat polycythemia vera. Silence Therapeutics’ cash reserves are projected to support operations until 2027, allowing continued investment in its RNAi pipeline. The company plans to advance its siRNA therapy, SLN548, targeting complement factor B, into Phase 1 trials in the latter half of 2025.
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