Enanta Pharma posts narrower-than-feared Q4 loss as expenses decline

Published 17/11/2025, 22:20
 Enanta Pharma posts narrower-than-feared Q4 loss as expenses decline

WATERTOWN, Mass. - Enanta Pharmaceuticals, Inc. (NASDAQ:ENTA) reported a narrower-than-expected fourth-quarter loss on Monday, as the clinical-stage biotechnology company benefited from reduced research and legal expenses. The company’s shares closed 6% higher.

Enanta posted a fourth-quarter loss of $0.87 per share, beating analyst expectations for a loss of $1.01 per share. Revenue came in at $15.13 million, slightly below the consensus estimate of $15.97 million but up from $14.6 million in the same period last year. The revenue increase was attributed to higher royalties from AbbVie’s hepatitis C virus regimen MAVYRET/MAVIRET.

Research and development expenses decreased to $23.8 million from $30.8 million in the year-ago quarter, primarily due to the timing of clinical trials in the company’s RSV programs. General and administrative expenses also fell to $9.7 million from $13.7 million, reflecting lower legal expenses related to the company’s patent infringement lawsuit against Pfizer and decreased stock-based compensation.

"This past quarter marked a pivotal period for Enanta, with significant progress across our virology and immunology programs," said Jay R. Luly, Ph.D., President and Chief Executive Officer at Enanta Pharmaceuticals. "These Phase 3-enabling results underscore zelicapavir’s ability to meaningfully reduce the duration of RSV symptoms."

The company highlighted several pipeline advancements, including the selection of EPS-3903 as its lead STAT6 inhibitor development candidate for type 2 immune-driven diseases and the nomination of EDP-978 as its KIT inhibitor clinical candidate for mast-cell driven diseases.

Enanta ended fiscal 2025 with $188.9 million in cash, cash equivalents and marketable securities. The company further strengthened its financial position in October with an upsized public offering that generated gross proceeds of $74.8 million. Management expects current resources, combined with retained royalty revenue, to fund operations into fiscal 2029.

For the full fiscal year 2025, Enanta reported revenue of $65.3 million, down from $67.6 million in fiscal 2024, and a net loss of $81.9 million, or $3.84 per share, compared to a net loss of $116.0 million, or $5.48 per share, in the previous year.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

Latest comments

Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers
© 2007-2025 - Fusion Media Limited. All Rights Reserved.