Gilead stock falls after CVS holds off adding HIV prevention shot to plans

Published 21/08/2025, 13:22
©  Reuters

Investing.com -- Gilead Sciences (NASDAQ:GILD) stock fell 2.7% in pre-market trading Thursday after reports that CVS Health (NYSE:CVS) will not add the company’s new HIV prevention drug, Yeztugo, to its commercial plans for now.

According to Reuters, CVS, which operates the largest U.S. pharmacy benefit manager, based its decision on "clinical, financial, and regulatory factors." The company also will not cover Yeztugo under its Affordable Care Act formularies, as its ACA preventive program follows recommendations from the U.S. Department of Health and Human Services.

This setback comes despite Gilead management’s previous confidence about Yeztugo’s coverage trajectory. The company had stated it was "well on our way to achieving 75% access for Yeztugo within six months and 90% within 12 months."

BMO Capital analyst Evan David Seigerman called the development "an incremental negative to GILD" but noted that "CVS coverage delays are not yet concerning for Yeztugo broad coverage goals." He pointed out that conversations with CVS are ongoing, and that the U.S. Preventative Services Task Force (USPSTF) has yet to make a determination on adding Yeztugo as a covered drug.

Mizuho (NYSE:MFG) analysts suggested that upcoming coverage decisions from UnitedHealth (NYSE:UNH) and Cigna (NYSE:CI) could now be more significant catalysts than previously thought. They noted that CVS appears to be "pushing back on price for the injection(s) either straight up or when compared to daily pills."

Yeztugo, administered as a bi-annual injection, has demonstrated strong efficacy in clinical trials for HIV prevention.

Latest comments

Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers
© 2007-2025 - Fusion Media Limited. All Rights Reserved.