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This article summarizes the most significant insider buys and sells from Thursday, September 4, 2025, for US stocks.
Top Insider Buys:
American Strategic Investment Co. (NASDAQ:NYC) saw notable insider purchases over two days. Entities associated with Nicholas S. Schorsch acquired a total of 664 shares of Class A common stock at prices ranging from $10.02 to $10.96, for a combined value of $7,029. These purchases come as the micro-cap company, valued at $28.82 million, faces challenges with its stock declining nearly 9% over the past week. Despite these difficulties, InvestingPro analysis suggests the stock may be undervalued.
Top Insider Sells:
Ionis Pharmaceuticals Inc (NASDAQ:IONS) reported significant insider selling activity. Patrick R. O’Neil, Executive Vice President, CLO & General Counsel, sold 90,400 shares of common stock over two days, fetching prices between $54.5148 and $61.42, for total proceeds of approximately $5.39 million. These sales were related to the exercise of stock options, where O’Neil acquired 89,900 shares at prices ranging from $32.6 to $53.77.
Ionis Pharmaceuticals Inc (NASDAQ:IONS) also saw its Chief Executive Officer, Monia Brett P, sell 206,914 shares of common stock for a total of $12,294,703. The sales occurred at weighted average prices between $59.119 and $61.0629 per share. This activity coincides with the stock trading near its 52-week high of $62.08 and showing remarkable momentum with a 39.2% return in the past week.
Carvana Co. (NASDAQ:CVNA) reported that Chief Executive Officer Ernest C. Garcia III, through trusts, sold 9,813 shares of Class A Common Stock for approximately $3.65 million. The sales were executed at prices ranging from $360.38 to $370.91 under a Rule 10b5-1 trading plan adopted in December 2024.
Microsoft (NASDAQ:MSFT) Chief Executive Officer Satya Nadella sold 149,205 shares of the company’s common stock for approximately $75.3 million. The sales were executed at prices ranging from $503.0039 to $507.558 per share. This activity occurs as Microsoft’s market capitalization stands at $3.77 trillion, with the stock showing strong momentum, gaining over 31% in the past six months.
INSMED Inc (NASDAQ:INSM) Chief Medical Officer Martina Flammer sold shares of common stock at prices ranging from $141.27 to $146.05, totaling $26.9 million. This transaction followed the exercise of stock options to acquire 175,646 shares at prices between $17.07 and $34.03.
Investors should stay tuned to insider trading activity as it can provide valuable insights into a company’s prospects. While insider buying may signal confidence in the company’s future, selling can occur for various reasons and doesn’t necessarily indicate a negative outlook. It’s essential to consider these transactions alongside other financial metrics and market conditions when making investment decisions.
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