BMO maintains Bristol-Myers $61 target after trial setback

Published 15/04/2025, 14:26
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On Tuesday, BMO Capital Markets sustained its Market Perform rating for Bristol-Myers Squibb Co. (NYSE:BMY) with a steady price target of $61.00. The decision follows the pharmaceutical company’s recent clinical trial setback. With a market capitalization of $104.5 billion and according to InvestingPro analysis, BMY is currently trading below its Fair Value, while maintaining a strong 4.8% dividend yield backed by 55 consecutive years of dividend payments. Bristol-Myers Squibb’s ODYSSEY-HCM Phase 3 trial for Camzyos, a drug intended to treat nonobstructive hypertrophic cardiomyopathy (nHCM), did not demonstrate the expected benefits, potentially complicating the company’s growth trajectory as it approaches the expiration of patents for some of its key drugs. Despite the setback, the company maintains robust financials with $48.3 billion in revenue and an impressive 75% gross profit margin. InvestingPro data reveals 12 additional key insights about BMY’s financial health and market position.

Evan David Seigerman of BMO Capital commented on the trial’s outcome, noting that the failure to show a statistically significant benefit in less-severe nHCM patients underscores the challenges of drug development in this area. The unsuccessful trial means that Bristol-Myers Squibb will not be able to pursue an opportunity for Camzyos in one-third of hypertrophic cardiomyopathy (HCM) patients who have the nonobstructive form of the disease.

Seigerman further explained that while this result is a disappointment, it does not affect the potential for Camzyos in treating obstructive HCM (oHCM), where no new safety concerns were identified in the trial’s findings. The focus now shifts to upcoming catalysts that need to deliver positive results to alter the narrative for Bristol-Myers Squibb, according to the analyst.

Bristol-Myers Squibb’s stock performance and investor sentiment could be influenced by the company’s ability to navigate the challenges posed by the loss of patent exclusivity for some of its products and the necessity for positive outcomes in its future clinical trials. The company’s strategy and response to these developments will be closely watched by investors and industry observers. Notably, InvestingPro analysis indicates the stock’s RSI suggests oversold territory, while analysts project profitability this year despite current challenges. For deeper insights into BMY’s valuation and growth prospects, investors can access the comprehensive Pro Research Report, available exclusively to InvestingPro subscribers.

In other recent news, Bristol-Myers Squibb announced that its Phase 3 ODYSSEY-HCM trial for Camzyos did not meet its primary endpoints for treating non-obstructive hypertrophic cardiomyopathy (nHCM). Despite the setback, the drug continues to show benefits for obstructive HCM, maintaining its established benefit-risk profile. Analysts have responded to these developments with mixed outlooks. Goldman Sachs downgraded Bristol-Myers Squibb from Buy to Neutral, citing challenges related to upcoming patent expirations, while UBS lowered its price target to $54, maintaining a Neutral rating due to anticipated revenue impacts. In contrast, BMO Capital Markets held a Market Perform rating with a $61 target, highlighting strong prescription growth for Cobenfy, a drug for schizophrenia. The UBS analysis also suggests that sales forecasts for key products like Eliquis and Revlimid might be underestimated, projecting higher than consensus sales figures. Meanwhile, Citi analyst Geoff Meacham maintained a Neutral rating, emphasizing the positive impact of Camzyos on obstructive HCM as a market opportunity. These developments suggest a complex landscape for Bristol-Myers Squibb as it navigates both challenges and opportunities in its portfolio.

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