Esperion stock holds Buy rating, $16 target from H.C. Wainwright

Published 11/02/2025, 13:34
Esperion stock holds Buy rating, $16 target from H.C. Wainwright

On Tuesday, H.C. Wainwright maintained a positive stance on Esperion Therapeutics (NASDAQ:ESPR) shares, reaffirming a Buy rating and a price target of $16.00. According to InvestingPro data, analyst targets for the stock range from $2.05 to $16.00, with the consensus recommendation leaning toward a moderate buy at 2.11 on a scale where 1 represents a strong buy. The firm’s analyst highlighted the recent subset analysis from the CLEAR Outcomes Trial, which was published in the Journal of the American Heart Association. In this analysis, bempedoic acid (BDA), a drug developed by Esperion, showed significant clinical benefits for a subpopulation of patients with a high cardiovascular (CV) risk and obesity.

The exploratory analysis focused on 6,179 patients from the CLEAR Outcomes Trial, representing 44.2% of the participants, who had a Body Mass Index (BMI) of 30 kg/m2 or higher. Within this group, 3,075 patients were given BDA while 3,104 received a placebo. Over a median follow-up period of 40.7 months, the results indicated a favorable outcome for those treated with BDA. InvestingPro subscribers can access detailed financial health metrics and 7 additional ProTips that provide crucial insights into Esperion’s market position.

H.C. Wainwright expects these findings to enhance the adoption of bempedoic acid in clinical practice. The firm anticipates that the drug will become the preferred next therapy for managing lipid levels and cardiovascular risk on a global scale. The analyst’s maintained price target reflects confidence in the drug’s potential and Esperion’s growth prospects.

Esperion Therapeutics focuses on the development of therapies to treat patients with elevated low-density lipoprotein cholesterol (LDL-C). Bempedoic acid is part of the company’s portfolio aimed at cardiovascular disease management. The company has shown impressive revenue growth of 187% over the last twelve months, reaching $295.45 million, as reported by InvestingPro. The positive results from the CLEAR Outcomes Trial subset analysis could play a crucial role in the drug’s commercial success and its integration into standard treatment protocols for patients with obesity and high CV risk. For comprehensive analysis including revenue forecasts and detailed financial metrics, investors can access the full Pro Research Report, available exclusively to InvestingPro subscribers.

In other recent news, Esperion Therapeutics has been quite active on the financial front. The company issued $100 million in new convertible notes, as well as secured a $150 million loan and issued an additional $100 million in notes, as part of a strategic financial restructuring. This move aims to repay a significant portion of its existing $265 million convertible debt, extending its maturity and enhancing Esperion’s financial flexibility. Analyst firm JMP Securities recently adjusted its price target for Esperion shares, lowering it to $4.00 from the previous $7.00, while maintaining a Market Outperform rating. Despite the reduction in the price target, JMP Securities’ outlook on Esperion remains optimistic. On the operational side, Esperion projected its research & development costs to be between $55 million to $65 million and selling, general, and administrative expenses to range from $160 million to $170 million for the fiscal year ending December 31, 2025. These recent developments indicate an active period for Esperion, both in terms of financial restructuring and operational forecasting.

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