Exelixis stock price target lowered to $46 at H.C. Wainwright on SCCHN trial halt

Published 12/08/2025, 12:42
Exelixis stock price target lowered to $46 at H.C. Wainwright on SCCHN trial halt

Investing.com - H.C. Wainwright lowered its price target on Exelixis (NASDAQ:EXEL) to $46.00 from $53.00 on Tuesday, while maintaining a Buy rating on the stock. According to InvestingPro data, analyst targets for the stock range from $36.00 to $60.00, with the company currently trading at $37.41 and showing signs of being undervalued.

The firm’s decision follows Exelixis’s announcement that it will not proceed to the Phase 3 portion of the STELLAR-305 trial, prompting H.C. Wainwright to remove risk-adjusted revenue projections for zanzalintinib in squamous cell carcinoma of the head and neck (SCCHN).

For the second quarter of 2025, Exelixis reported diluted net income of $0.65 per share, exceeding H.C. Wainwright’s previous forecast of $0.57 per share. The company generated $568.3 million in revenue, with cabozantinib sales accounting for $520.0 million.

Research and development expenses came in at $200.4 million, below the firm’s estimate of $233.5 million, while selling, general and administrative expenses were $134.9 million, slightly above the projected $129.0 million.

H.C. Wainwright has revised its full-year 2025 net earnings projection for Exelixis to $2.30 per share, up from its prior estimate of $2.26 per share, despite the price target reduction related to the trial decision.

In other recent news, Exelixis Inc . reported its second-quarter 2025 earnings, achieving an earnings per share (EPS) of $0.75, which exceeded analysts’ expectations of $0.64. The company’s revenue, however, was slightly below forecasts, coming in at $568 million compared to the projected $578.46 million. Despite the revenue shortfall, Exelixis’ strategic advancements and earnings beat have maintained positive investor sentiment. RBC Capital lowered its price target for Exelixis to $45.00 from $50.00, citing missed revenue expectations as a factor for potential near-term stock weakness. Truist Securities also reduced its price target to $49.00 from $56.00 following mixed results, noting that Cabometyx sales were below both Wall Street and Truist’s estimates. On the other hand, Stifel raised its price target to $41.00 from $38.00 due to increased success estimates for Exelixis’ zanza in metastatic colorectal cancer. JMP Securities reiterated its Market Outperform rating and maintained a $50.00 price target, emphasizing solid volume growth and long-term sales potential for cabozantinib. These developments highlight the varied analyst perspectives on Exelixis amidst its recent financial performance.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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