H.C. Wainwright lowers Cardiff Oncology stock price target on trial data

Published 06/08/2025, 13:00
H.C. Wainwright lowers Cardiff Oncology stock price target on trial data

Investing.com - H.C. Wainwright has reduced its price target on Cardiff Oncology (NASDAQ:CRDF) to $10.00 from $18.00 while maintaining a Buy rating on the stock. Currently trading at $2.57, the clinical-stage biotech company has a market capitalization of $171 million, with analyst targets ranging from $3.50 to $19.00.

The adjustment follows Cardiff Oncology’s presentation of updated results from its CRDF-004 trial last week, which showed that onvansertib 30mg plus standard of care achieved a 49% confirmed objective response rate (n=37) compared to 30% for the standard of care arm (n=37).

This 19% delta represents a decline from initial results presented last year, which had shown a 64% objective response rate (n=11) for onvansertib 30mg plus standard of care versus 33% for the standard of care arm (n=9).

H.C. Wainwright noted ECOG performance status imbalances between the treatment groups, with 61% of patients in the combination arm having ECOG 0 status compared to only 35% in the control arm.

Due to these factors, the firm has reduced its probability of approval for onvansertib to 25% from the previous 40%, despite early progression-free survival data suggesting a benefit in the preliminary dataset.

In other recent news, Cardiff Oncology Inc reported its second-quarter earnings, which fell short of analyst expectations. The company posted a loss of $0.21 per share, while analysts had projected a loss of $0.19 per share. Despite the earnings miss, Cardiff Oncology’s revenue surpassed estimates, coming in at $120,000 compared to the anticipated $96,430. The company’s operating expenses rose to $14.9 million, an increase from $12.7 million in the same period last year. These recent developments have drawn significant attention from investors and analysts alike.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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