JMP Securities maintains Cytokinetics stock with $78 target

Published 07/02/2025, 11:22
JMP Securities maintains Cytokinetics stock with $78 target

On Thursday, JMP Securities reiterated its Market Outperform rating and $78.00 price target for Cytokinetics shares (NASDAQ:CYTK). This affirmation comes despite the stock experiencing a significant drop on Wednesday, when it fell 8.4% compared to the 1.4% decline in the XBI biotech index. Currently trading at $46.17, near its 52-week low of $44.49, InvestingPro analysis indicates the stock is currently overvalued. Analyst targets range from $60 to $120, reflecting diverse market expectations for this $5.45 billion market cap company. The decrease in Cytokinetics’ stock value was attributed to market reactions following Bristol Myers Squibb’s (NYSE:BMY) earnings call, during which the company mentioned that the FDA is contemplating a less stringent Risk Evaluation and Mitigation Strategy (REMS) for its drug CAMZYOS.

JMP Securities addressed the market’s response, suggesting that the implications of this potential regulatory decision for Cytokinetics’ competitive position might be misinterpreted. According to the firm, even if CAMZYOS were to have similar ECHO monitoring requirements as aficamten, Cytokinetics’ drug, the REMS programs for both treatments would likely remain substantially different. InvestingPro data shows the company maintains strong liquidity with a current ratio of 9.28, though it operates with moderate debt levels. For deeper insights into Cytokinetics’ competitive position and financial health, InvestingPro offers comprehensive analysis with 10+ additional ProTips. JMP Securities believes that the differences would be in favor of aficamten, Cytokinetics’ cardiac myosin inhibitor.

Cytokinetics has been developing aficamten for patients with hypertrophic cardiomyopathy, a condition characterized by thickened heart muscle that can obstruct blood flow. The REMS program for such a medication typically includes strategies to ensure that the drug is prescribed and used safely, given the potential risks associated with its use.

The analyst from JMP Securities expressed confidence in the prospects of aficamten, despite the perceived competitive pressure from Bristol Myers Squibb’s CAMZYOS. The firm’s maintained price target reflects an anticipation of continued performance and potential market success for Cytokinetics’ offering. With earnings scheduled for February 20, investors can access detailed financial analysis and Fair Value estimates through InvestingPro’s exclusive research reports, available for over 1,400 US stocks.

Investors and market watchers will be closely monitoring both Cytokinetics and the FDA’s decisions regarding REMS programs, as these could have significant implications for the marketing and use of new cardiac therapies. The biotech sector often sees stock volatility in response to regulatory news, with company valuations heavily influenced by such developments.

In other recent news, Cytokinetics has made significant strides in both its philanthropic and business endeavors. The company recently awarded $100,000 in grants to five patient advocacy organizations focused on hypertrophic cardiomyopathy (HCM) and heart failure. The grants aim to enhance communication strategies and engage more effectively with the patient communities. Among the recipients are the Italian Association of Cardiomyopathies (AICARM APS) and the HeartBrothers Foundation, all of which plan to use the funding for a variety of outreach and education initiatives.

On the business front, Cytokinetics’ stock was initiated with a Buy rating by Stifel analysts, citing a compelling investment case due to potential catalysts ahead, including the company’s leading drug candidate, aficamten. Furthermore, H.C. Wainwright reaffirmed a Buy rating for Cytokinetics, highlighting the company’s anticipated corporate milestones in 2025 and its Vision 2030 strategic plan. The company’s top priority is the approval and commercial launch preparations for aficamten in obstructive hypertrophic cardiomyopathy (oHCM).

In addition, Piper Sandler identified Cytokinetics as one of the six stocks with de-risked Phase 3 readouts or interim analyses expected in 2025. Lastly, Sanofi (NASDAQ:SNY) recently acquired exclusive rights to develop and commercialize aficamten in Greater China, which could lead to up to $150 million in development and commercial milestone payments for Cytokinetics. These are the recent developments that investors should be aware of.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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