Truist maintains Buy on Kymera stock, reiterates $53 target

Published 09/05/2025, 19:44
Truist maintains Buy on Kymera stock, reiterates $53 target

On Friday, Truist Securities sustained its Buy rating and $53.00 price target for Kymera Therapeutics (NASDAQ:KYMR) stock, prompted by the company’s first-quarter results. The stock, currently trading at $30.58, has shown significant volatility with a -12.78% return over the past week. According to InvestingPro analysis, the company appears slightly undervalued based on its Fair Value model. The biotechnology firm’s update highlighted the progress of KT-579, an innovative oral treatment targeting the IRF5 protein, which is implicated in a variety of inflammatory and autoimmune diseases such as rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and systemic lupus erythematosus (SLE).

Truist Securities expressed increased optimism about Kymera’s prospects after the business update, citing the potential for KT-579 to complement existing treatments for inflammatory and autoimmune conditions. The analysts pointed to the biological evidence, genome-wide association studies, and preclinical models that underscore the significance of the IRF5 protein in these diseases.

Additionally, the company’s strategic decision to discontinue the development of KT-295, a TYK2 degrader, was noted. This move, which did not impact Truist’s valuation model, is expected to allow Kymera to focus more on advancing its STAT6 program and the development of IRF5. This refocusing of resources is projected to extend the company’s cash runway into the first half of 2028, an extension from the previously anticipated mid-2027, according to management. InvestingPro data shows the company maintains a strong liquidity position with a current ratio of 7.53 and holds more cash than debt on its balance sheet.

Kymera’s near-term attention remains on KT-621, with the investment firm encouraging investors to maintain their positions in anticipation of high-value data expected to be released in June. The company’s first-quarter update has reinforced confidence in its pipeline and strategic direction, as it continues to develop treatments for a range of serious diseases. Analyst consensus remains bullish, with price targets ranging from $41 to $97. For deeper insights into Kymera’s financial health and growth prospects, including additional ProTips and comprehensive valuation metrics, check out the detailed Pro Research Report available on InvestingPro.

In other recent news, Kymera Therapeutics has reported its financial performance for the first quarter of 2025, revealing a narrower-than-expected loss. The company’s earnings per share (EPS) stood at -0.82, surpassing the forecasted -0.89. Additionally, Kymera’s revenue reached $22.1 million, significantly exceeding the anticipated $11.38 million. In terms of strategic moves, Kymera has decided to pause the development of its TYK2 degrader program, KT295, to prioritize resources towards its STAT6 and IRF5 programs, which are expected to drive future growth.

The company also achieved a preclinical milestone with its IRAK4 program, resulting in a $20 million payment from Sanofi (NASDAQ:SNY). Analysts have shown interest in Kymera’s advancements, particularly in its STAT6 degrader program, which aims to provide an oral alternative to biologics like dupilumab. The company plans to initiate Phase IIb trials for this program in atopic dermatitis (AD) and asthma starting in late 2025 and early 2026, respectively. Kymera’s strategic focus on targeted protein degradation technology continues to align with industry trends, addressing substantial market opportunities in immune-inflammatory diseases.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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