Truist maintains Kymera Therapeutics stock buy rating and $35 target

Published 12/05/2025, 14:02
Truist maintains Kymera Therapeutics stock buy rating and $35 target

On Monday, Truist Securities expressed a continued positive stance on Kymera Therapeutics (NASDAQ:KYMR), maintaining a Buy rating and a price target of $35.00. Currently trading at $30.07, the stock appears undervalued according to InvestingPro analysis, with analyst targets ranging from $38 to $97. The endorsement comes after the company’s first-quarter 2025 business update, which introduced KT-579, an innovative oral degrader targeting the IRF5 protein. IRF5 is significant in various inflammatory and autoimmune diseases, such as rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and systemic lupus erythematosus (SLE). InvestingPro data shows the company maintains a strong financial position with a current ratio of 8.49, indicating robust liquidity to support its research programs.

The company’s research and genetic association studies, coupled with preclinical models, suggest that KT-579 could complement existing treatments for these conditions. Although KT-579 is in the early stages of development, Truist Securities sees potential in its progression.

Kymera Therapeutics has also decided to discontinue the development of KT-295, a TYK2 degrader, to concentrate on the advancement of the STAT6 program and the development of IRF5-targeting therapies. This strategic move is expected to extend the company’s cash runway into the first half of 2028, an extension from the previously projected mid-2027, according to management. InvestingPro Tips highlight that the company holds more cash than debt on its balance sheet, though investors should note the stock has experienced significant volatility recently, with a -10.45% return over the past week. For deeper insights into Kymera’s financial health and 8 additional ProTips, consider accessing the comprehensive Pro Research Report.

The focus for the near term remains on KT-621, with high-value data anticipated to be released in June. Truist Securities recommends investors to continue buying shares in Kymera Therapeutics in anticipation of the upcoming data release. The company’s strategic refocusing and pipeline expansion appear to position it well for future developments in the treatment of inflammatory and autoimmune diseases.

In other recent news, Kymera Therapeutics reported a better-than-expected financial performance for the first quarter of 2025, with earnings per share (EPS) at -0.82, surpassing the forecast of -0.89. The company’s revenue also exceeded projections, reaching $22.1 million against the expected $11.38 million. Following these results, BTIG analyst Jeet Mukherjee adjusted the price target for Kymera to $55 from $60, maintaining a Buy rating. Mukherjee noted that the strategic shift to focus on the IRF5 program, following the discontinuation of the TYK2 degrader, could position Kymera well in addressing novel indications. Truist Securities also retained a Buy rating and a $53 price target, reflecting optimism about the potential of KT-579, an oral treatment targeting the IRF5 protein. The company is expected to benefit financially from these strategic shifts, extending its cash runway into the first half of 2028. These developments are part of Kymera’s ongoing efforts to advance its immunology pipeline, with significant updates expected in the coming months.

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