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Barinthus Bio names Leon Hooftman as new CMO

EditorBrando Bricchi
Published 01/05/2024, 19:00
BRNS
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OXFORD, United Kingdom - Barinthus Biotherapeutics plc (NASDAQ: BRNS), a biopharmaceutical company focused on T cell immunotherapies for chronic diseases and cancer, today announced the appointment of Dr. Leon Hooftman as Chief Medical Officer, effective from the beginning of June 2024. Dr. Hooftman, who holds an MD from Utrecht State University and has specialist training from Cambridge and London, brings over 25 years of experience in drug development across various therapeutic areas, including oncology and infectious diseases.

CEO Bill Enright welcomed Dr. Hooftman, highlighting his extensive background in clinical studies and his previous senior management roles at companies like Roche and UCB Celltech. Dr. Hooftman expressed his enthusiasm for joining Barinthus Bio at a significant phase of the company's growth, noting the promising pipeline of T cell immunotherapeutic candidates.

Dr. Hooftman's R&D portfolio includes contributions to the development of several novel agents, such as mycophenolate mofetil for transplantation, rituximab for Non-Hodgkin’s Lymphoma, gemtuzumab ozogamycin for Leukemia, and lipid complex amphotericin B for serious fungal infections. His recent position at ISA Pharmaceuticals, a specialist immune-oncology company, adds to his credentials in the biotech field.

Barinthus Bio, formerly known as Vaccitech plc, is advancing a pipeline of product candidates, including potential treatments for chronic HBV infection, high-risk HPV infection, celiac disease, and recurrent prostate cancer. The company aims to address diseases with unmet medical needs through its proprietary platform technologies: ChAdOx, MVA, and SNAP.

This announcement is based on a press release statement, and forward-looking statements contained in the release involve risks and uncertainties that could cause actual results to differ materially from those anticipated. These include the success, cost, and timing of the company's development activities and clinical trials, regulatory developments, and the ability to fund operations and access capital. The appointment of Dr. Hooftman is seen as a strategic move to strengthen the company's leadership in advancing its therapeutic candidates.

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InvestingPro Insights

In light of Barinthus Biotherapeutics plc's recent strategic appointment of Dr. Leon Hooftman as Chief Medical Officer, investors and industry observers are keenly watching the company's financial health and market performance. According to InvestingPro data, Barinthus Bio currently holds a market capitalization of 79.79 million USD, a notable figure for a biopharmaceutical firm of its size. However, the company's financial metrics indicate significant challenges, with a revenue for the last twelve months as of Q4 2023 reported at 0.8 million USD, reflecting a substantial decline of 98.21%.

The company's gross profit margin stands at a concerning -5495.26% for the same period, underscoring the financial hurdles Barinthus Bio faces. The stock price has also experienced volatility, with a 1-week price total return of -18.33% and a 6-month price total return of -54.14%, suggesting that investor sentiment may be affected by the company's current financial trajectory.

InvestingPro Tips offer additional insights, noting that while Barinthus Bio holds more cash than debt, which is a positive sign of liquidity, it is quickly burning through cash. This could be a red flag for investors considering the company's ability to sustain its operations and research endeavors. Moreover, two analysts have revised their earnings downwards for the upcoming period, and the stock has taken a significant hit over the last week. These factors may be crucial for those looking to understand the potential risks and opportunities associated with investing in Barinthus Bio.

For investors seeking a deeper analysis, there are over 10 additional InvestingPro Tips available, which can provide more nuanced guidance on Barinthus Bio's financial and market performance. Access these tips and more detailed metrics by visiting https://www.investing.com/pro/BRNS, and consider using the special coupon code PRONEWS24 to get an extra 10% off a yearly or biyearly Pro and Pro+ subscription.

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