Barinthus Biotherapeutics plc, a clinical-stage biopharmaceutical company, focuses on developing immunotherapeutic drug candidates for treating auto-immune and inflammatory diseases. Its lead candidate is VTP-1000, which is in Phase 1 clinical trial to restore immune non-responsiveness to gluten in patients with celiac disease. The company is also developing VTP-300, an immunotherapeutic targeting chronic hepatitis B virus infection; VTP-200, a potential non-invasive treatment for persistent high-risk human papillomavirus; VTP-850, an immunotherapeutic candidate for prostate cancer; VTP-600, an immunotherapeutic candidate targeting MAGE-A3 and NY-ESO1 antigens; VTP-500, a prophylactic vaccine candidate to prevent middle east respiratory syndrome; VTP-400, a prophylactic vaccine candidate for shingles; and Vaxzevria, a prophylactic vaccine for the prevention of COVID-19 infection. The company was formerly known as Vaccitech plc and changed its name to Barinthus Biotherapeutics plc in November 2023. Barinthus Biotherapeutics plc was founded in 2016 and is headquartered in Didcot, the United Kingdom.
HBV Breakthrough | BRNS sharpens focus on Hepatitis B Virus treatments, positioning itself to address a significant unmet medical need in a competitive landscape |
Financial Challenges | Negative EPS forecasts and recent workforce reduction highlight BRNS's struggle for profitability, with cash runway extended to Q2 2026 |
Strategic Pivot | Explore BRNS's agile response to market trends, prioritizing HBV and Celiac disease research while streamlining operations |
Market Potential | Analyst price targets range from $3 to $7, reflecting varied outlooks on BRNS's ability to capitalize on its focused pipeline and industry trends |
Metrics to compare | BRNS | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipBRNSPeersSector | |
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P/E Ratio | −1.1x | −4.3x | −0.5x | |
PEG Ratio | −0.11 | −0.02 | 0.00 | |
Price/Book | 0.6x | 4.1x | 2.6x | |
Price / LTM Sales | 4.8x | 9.2x | 3.2x | |
Upside (Analyst Target) | 155.7% | 151.9% | 40.5% | |
Fair Value Upside | Unlock | 15.7% | 4.4% | Unlock |