Fulcrum Therapeutics stock hits 52-week low at $2.85

Published 11/03/2025, 15:32
Fulcrum Therapeutics stock hits 52-week low at $2.85

Fulcrum Therapeutics Inc . (NASDAQ:FULC) shares have tumbled to a 52-week low, touching down at $2.85, as the biotechnology firm faces a challenging market environment. According to InvestingPro data, the stock’s high volatility is reflected in its beta of 2.2, while technical indicators suggest oversold conditions. This latest price level reflects a significant downturn from previous periods, marking a stark contrast to the company’s performance over the past year. Investors have witnessed a dramatic -73.67% change in the stock’s value year-over-year, with a concerning -66.44% decline in just the past six months. Despite these challenges, analysts maintain price targets ranging from $2 to $14, suggesting potential recovery opportunities. The steep decline to this 52-week low point has raised concerns among shareholders about the company’s near-term prospects and the broader biotech sector’s resilience amidst a fluctuating market landscape. For deeper insights into FULC’s valuation and growth prospects, including exclusive ProTips and comprehensive analysis, visit InvestingPro.

In other recent news, Fulcrum Therapeutics, Inc. has announced the termination of two significant collaboration agreements. The first termination involves an agreement with MyoKardia (NASDAQ:MYOK), a subsidiary of Bristol-Myers Squibb Company (NYSE:BMY), which was initially established to develop therapies for genetically defined cardiomyopathies. This termination will take effect on June 26, 2025, ending Fulcrum’s entitlement to future milestone payments, royalties, or research cost reimbursements from MyoKardia. In a similar development, Fulcrum received a termination notice from Genzyme Corporation, a Sanofi (NASDAQ:SNY) subsidiary, concerning the commercialization rights for losmapimod outside the United States. This agreement will officially end on April 17, 2025, after which Fulcrum will no longer receive milestone payments, royalties, or development cost reimbursements from Sanofi. Sanofi had previously made an $80 million upfront payment to Fulcrum, with potential additional payments up to $975 million based on regulatory and sales milestones. These recent developments have been disclosed as part of Fulcrum’s regular SEC filings, ensuring transparency for investors and stakeholders.

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