Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecules to improve the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its clinical-stage product candidate is pociredir, a fetal hemoglobin inducer, which is in phase 1b clinical trial for the treatment of sickle cell disease and beta-thalassemia. The company also discovers drug targets for potential treatment inherited aplastic anemias, such as of diamond-blackfan anemia, shwachman-diamond syndrome, and fanconi anemia, as well as novel fetal hemoglobin inducers, fibrotic disorders, and cardiomyopathies which is in preclinical trial. It has collaboration and license agreement with MyoKardia, Inc. to identify biological targets that are capable of modulating genes of interest with relevance to cardiomyopathies; and licensce agreement with CAMP4 which includes certain small molecule compounds, composition of matter and method of use patent rights, and know-how to research, develop, manufacture, use, and commercialize; and Sanofi for the development and commercialization of losmapimod, an oral small molecule being investigated for the treatment of facioscapulohumeral muscular dystrophy. Fulcrum Therapeutics, Inc. was Incorporated in 2015 and is headquartered in Cambridge, Massachusetts.
Pipeline Pivot | Explore Fulcrum's strategic shift following losmapimod's Phase III trial setback, focusing on pociredir for Sickle Cell Disease and early-stage programs |
Financial Resilience | Despite recent challenges, Fulcrum maintains strong liquidity with more cash than debt and a healthy current ratio of 18.44 |
Market Volatility | Fulcrum's stock experiences significant fluctuations, with analyst price targets ranging from $2 to $14, reflecting diverse views on future prospects |
Growth Potential | Delve into Fulcrum's proprietary pipeline and expertise in rare genetic disorders, which could lead to valuable partnerships and licensing agreements |
Metrics to compare | FULC | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipFULCPeersSector | |
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P/E Ratio | −4.8x | 3.4x | −0.5x | |
PEG Ratio | 0.02 | 0.16 | 0.00 | |
Price/Book | 1.6x | 1.3x | 2.6x | |
Price / LTM Sales | - | 2.4x | 3.3x | |
Upside (Analyst Target) | 76.2% | 43.7% | 43.4% | |
Fair Value Upside | Unlock | 33.0% | 7.1% | Unlock |