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NEW YORK - Nuvectis Pharma, Inc. (NASDAQ:NVCT), a clinical-stage biopharmaceutical company with a market capitalization of $151 million, announced Thursday the appointment of Juan Sanchez, MD, to its Board of Directors as it advances its oncology drug development programs. According to InvestingPro data, the company maintains a strong financial position with more cash than debt on its balance sheet.
Dr. Sanchez most recently served as Vice President of Corporate Communications and Investor Relations at Intra-Cellular Therapies until its acquisition by Johnson & Johnson for $14.6 billion in April 2025.
The appointment comes as Nuvectis prepares to begin its Phase 1b program for NXP900, an oral small molecule inhibitor of the SRC Family of Kinases that has completed Phase 1a dose escalation studies.
"I am pleased to join the Nuvectis Board at this pivotal time for the Company," Dr. Sanchez said in the press release.
Dr. Sanchez brings over 30 years of experience spanning clinical practice, Wall Street research, and biopharmaceutical executive leadership. During his tenure at Intra-Cellular Therapies, which began in 2014, he contributed to the development and commercialization of CAPLYTA (lumateperone). Prior to that, he served as a managing director of healthcare equity research at Ladenburg Thalmann & Co. and Punk, Ziegel & Co.
Nuvectis is developing precision medicines for oncology, with its lead program NXP900 designed to inhibit both catalytic and scaffolding functions of the SRC kinase. The company is also evaluating next steps for NXP800, an oral GCN2 activator that has shown anti-cancer activity in recurrent, platinum-resistant, ARID1a-mutated ovarian cancer.
The information in this article is based on a company press release statement. For deeper insights into Nuvectis’s financial health and growth potential, InvestingPro subscribers have access to over 30 additional financial metrics and exclusive analysis tools, including detailed Fair Value calculations and expert ProTips.
In other recent news, Nuvectis Pharma has initiated its Phase 1b program for the cancer drug NXP900 following a successful dose escalation study in patients with advanced solid tumors. This program includes a single-agent component currently underway, targeting specific genetic alterations in non-small cell lung cancer, mesothelioma, renal cancer, and other tumors with Hippo Pathway alterations. Meanwhile, Nuvectis has decided to halt further development of its NXP800 drug candidate for ovarian cancer due to limited progress, despite some clinical activity observed in a Phase 1b study.
Additionally, Nuvectis completed a drug-drug interaction study for NXP900, classifying it as a weak inhibitor of the CYP3A enzyme, which supports its potential use in combination with other cancer treatments. In terms of financial projections, H.C. Wainwright lowered the price target for Nuvectis Pharma from $15 to $10, maintaining a Buy rating. This adjustment reflects the removal of NXP800 from the firm’s projections, focusing instead on U.S. opportunities for NXP900. These developments highlight Nuvectis Pharma’s strategic focus on advancing NXP900 and optimizing its clinical assets.
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