Quoin reports progress in pediatric skin disorder study

Published 14/05/2025, 12:38
Quoin reports progress in pediatric skin disorder study

ASHBURN, Va. - Quoin Pharmaceuticals Ltd. (NASDAQ: QNRX), a small-cap biotech company currently valued at $3.74 million, has announced positive initial results from its ongoing clinical study for the treatment of Pediatric Peeling Skin Syndrome (PSS) using its investigational drug QRX003. According to InvestingPro data, the company maintains a healthy balance sheet with more cash than debt, positioning it well for continued clinical development. The study showed significant improvement in the patient’s skin condition after 12 weeks of treatment.

The clinical data revealed a two-grade improvement in both the Investigator’s Global Assessment (IGA) and the Modified Ichthyosis Area Severity Index (M-IASI), indicating a shift from severe to mild symptoms. Additionally, the Children’s Dermatology Life Quality Index (CDLQI) scores, which measure the impact of skin disease on quality of life, also demonstrated a notable improvement. Despite recent market volatility, with the stock showing a -70% return over the past six months, the company maintains a current ratio of 3.57, indicating strong ability to meet short-term obligations.

The patient has been responding well to QRX003 with no adverse events reported, and treatment is expected to continue with further assessment after 24 weeks. The positive outcomes from these clinical endpoints suggest a distinct enhancement in the patient’s quality of life.

Quoin’s CEO, Dr. Michael Myers, expressed optimism about the initial data, which may represent the first formal clinical study for PSS, a rare genetic skin disorder characterized by chronic skin peeling, pain, and itching. There is currently no approved treatment for PSS, and patients typically manage symptoms with over-the-counter products.

The company plans to expand the study to include more pediatric subjects in different countries and is also advancing QRX003 in late-stage clinical studies for Netherton Syndrome, another rare skin condition. The potential for QRX003 to be the first regulatory-approved treatment for PSS is a significant opportunity for Quoin.

Quoin Pharmaceuticals focuses on developing treatments for rare and orphan diseases, with a pipeline that includes potential therapies for various conditions such as Scleroderma and Epidermolysis Bullosa.

This report is based on a press release statement from Quoin Pharmaceuticals, and the information reflects the company’s current expectations and projections. The forward-looking statements in the press release are not guarantees of future performance and are subject to risks and uncertainties that could cause actual results to differ materially. Analyst price targets range from $50.40 to $350.00, reflecting significant upside potential from current levels. For deeper insights into Quoin’s financial health and growth prospects, including 12 additional ProTips and comprehensive valuation metrics, visit InvestingPro.

In other recent news, Quoin Pharmaceuticals Ltd. announced that it has regained compliance with Nasdaq’s minimum bid price requirement, a crucial development for maintaining its listing on the exchange. This follows the company’s strategic adjustment of its American Depositary Shares (ADS) ratio, changing from one ADS representing one Ordinary Share to one ADS representing twenty Ordinary Shares. The move was designed to meet Nasdaq’s $1.00 minimum bid price requirement. Additionally, Quoin Pharmaceuticals has reported positive clinical data from its ongoing Pediatric Netherton Syndrome study, highlighting the effectiveness of its treatment, QRX003, in maintaining nearly complete skin healing after six weeks. The company is also seeking a U.S. patent for QRX003, which aims to treat rare skin diseases, including Netherton Syndrome. Quoin’s CEO, Dr. Michael Myers, indicated that the patent could extend protection until 2045, covering multiple rare conditions. Furthermore, the company has filed a patent application that includes Peeling Skin Syndrome, with ongoing clinical trials in various locations. These developments reflect Quoin Pharmaceuticals’ commitment to advancing treatments for rare and orphan diseases.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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