Senti Bio appoints new scientific advisory board member

SOUTH SAN FRANCISCO, Calif. - Senti Biosciences, Inc. (NASDAQ: SNTI), a biotechnology firm specializing in cell and gene therapies, announced the addition of James B. Trager, Ph.D., to its Scientific Advisory Board (SAB) today. According to InvestingPro data, the company, currently valued at $81 million, maintains a strong liquidity position with a current ratio of 4.49, though it faces challenges with cash burn rates. Dr. Trager, a seasoned biotech leader with over 25 years of experience in cellular therapy development for cancer, is expected to bring valuable expertise to Senti Bio's oncology programs.

Dr. Trager's career has been marked by his role in the development of multiple clinical candidates and the advancement of novel cellular and biologic therapies. His previous positions include Chief Scientific Officer at Nkarta Therapeutics and Vice President of Research and Product Development at Dendreon Pharmaceuticals, Inc. The appointment comes as Senti Bio's stock has shown significant momentum, with a 48% price increase over the past six months, despite current trading levels suggesting the stock is slightly overvalued based on InvestingPro's Fair Value analysis. He has also been involved in the academic community, serving as an advisor for Shoreline Community College Immunotherapy Biohub and SPARK at Stanford.

Senti Bio's CEO, Timothy Lu, MD, PhD, expressed confidence that Dr. Trager's leadership experience and scientific acumen will be instrumental as the company progresses with its potentially transformative oncology therapies. Senti Bio's proprietary Gene Circuit platform has shown promise in addressing the challenge of precisely targeting cancer cells while sparing healthy ones.

The company's lead program, SENTI-202, is targeting hematologic cancers and is in Phase I clinical trials. Dr. Trager's appointment is expected to support the advancement of this and other product candidates in Senti Bio's pipeline. With the next earnings report due on May 9, 2025, analysts maintain a strong buy consensus, setting a target price of $12 per share. InvestingPro subscribers can access additional insights, including 8 more ProTips and detailed financial health metrics that help evaluate the company's growth potential. The company's technology has also demonstrated potential applications in T cells and other cell and gene therapy modalities, with ongoing efforts to explore these capabilities further through partnerships.

This move by Senti Bio underscores the company's commitment to improving treatments for incurable diseases by enhancing the precision and control of cell and gene therapies. The information regarding Dr. Trager's appointment and Senti Bio's scientific advancements is based on a press release statement.

In other recent news, Senti Biosciences, Inc. announced its participation in Webull's Corporate Connect Service to enhance communication with shareholders. The company aims to use this platform to keep investors informed about corporate updates, including earnings and product developments. Senti Bio's lead candidate, SENTI-202, is in clinical development, showing promising results in treating acute myeloid leukemia. In a strategic move, Senti Bio appointed Feng Hsiung to its Board of Directors, expecting his extensive experience to contribute to the company's growth. Additionally, the company granted stock options to new employees, including Chief Financial Officer Jay Cross, under its 2022 Inducement Equity Plan.

Senti Biosciences also received shareholder approval for amendments to its 2022 Equity Incentive Plan, allowing for increased shares to incentivize employees and directors. The plan's extension aims to align with the company's long-term goals. Furthermore, Jay Cross and Faraz Siddiqui have joined the leadership team as CFO and Senior Vice President of Technical Operations, respectively, to support financial strategy and operations. These developments reflect Senti Biosciences' ongoing efforts to strengthen its leadership and financial structure while advancing its clinical pipeline.

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