SONN stock touches 52-week low at $1.28 amid market challenges

Published 28/03/2025, 14:50
SONN stock touches 52-week low at $1.28 amid market challenges

In a challenging market environment, SONN (Sonnet BioTherapeutics Holdings (NASDAQ:SONN), Inc.) stock has reached a 52-week low, trading at $1.28. With a market capitalization of just $4 million, the company’s shares have declined over 90% in the past year. According to InvestingPro analysis, SONN currently appears undervalued compared to its Fair Value. The biopharmaceutical company, which focuses on innovative treatments for serious medical conditions, has faced significant headwinds over the past year, mirroring the struggles of the broader biotech sector. This new low underscores a period of volatility and investor caution, as the industry grapples with regulatory hurdles and a shifting economic landscape. Despite these challenges, InvestingPro data shows the company maintains a healthy balance sheet with more cash than debt and a current ratio of 2.15. Subscribers can access 12 additional ProTips and comprehensive financial metrics to make more informed investment decisions in this volatile sector.

In other recent news, Sonnet BioTherapeutics Holdings, Inc. has reported promising early results from its Phase 1 SB101 clinical trial for the drug SON-1010 in combination with trabectedin for treating advanced soft-tissue sarcoma. The Safety Review Committee found no unexpected toxicities among the first seven patients treated at the maximum tolerated dose, with mild or moderate adverse events reported. Furthermore, Sonnet announced the receipt of a Notice of Allowance from the USPTO for a new patent related to its IL-18 variant protein, IL-18BPR, which strengthens its intellectual property position in cancer treatment. The company is also advancing its Antibody Drug Conjugate (ADC) platform, which demonstrated similar tumor reduction activity to existing treatments in preclinical studies without detectable toxicity.

Sonnet has appointed Stephen J. McAndrew, Ph.D., as its new Chief Business Officer, who will focus on business development and licensing strategies. The company is expanding its Phase 1 trial to include a new cohort combining SON-1010 with trabectedin, targeting patients with unresectable, metastatic liposarcoma or leiomyosarcoma. This expansion aims to enhance trabectedin’s therapeutic effects with SON-1010’s immune-oncology properties. Sonnet’s CEO, Pankaj Mohan, Ph.D., highlighted the potential market opportunity for trabectedin and the unmet medical need in sarcoma treatment. The company believes these developments could pave the way for a larger Phase 2 study and potential partnerships.

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