Cantor Fitzgerald initiates Vaxcyte stock with Overweight rating

Published 22/04/2025, 13:24
Cantor Fitzgerald initiates Vaxcyte stock with Overweight rating

Tuesday, shares of Vaxcyte (NASDAQ:PCVX) received a new Overweight rating from Cantor Fitzgerald as the firm initiated coverage on the biotechnology company. The decision comes after Vaxcyte demonstrated promising VAX-31 pneumococcal conjugate vaccine (PCV) data in adults last fall. Despite facing challenges with mixed VAX-24 pediatric data and shifts in U.S. vaccine policy, Cantor Fitzgerald remains optimistic about the company’s long-term prospects. According to InvestingPro data, analysts have set price targets ranging from $65 to $163, reflecting significant potential upside from current levels.

Cantor Fitzgerald’s analysis points out that Vaxcyte’s programs are years away from regulatory review, with the adult VAX-31 expected in 2027 and the pediatric strategy projected for 2029. The firm suggests that the current leadership and policy environment are likely to change by the time Vaxcyte’s products come under review, which could positively impact the company’s trajectory. InvestingPro analysis reveals the company maintains a strong financial health score, with two key tips highlighting its solid balance sheet position. Subscribers can access 8 additional exclusive insights about PCVX’s financial condition.

Vaxcyte’s position in the pneumococcal conjugate vaccine market, which is valued at over $8 billion, appears to be strong due to the robust data from the adult VAX-31 trials. Cantor Fitzgerald also notes that Vaxcyte has two viable options for advancing pediatric vaccines—VAX-31 and a dose-optimized VAX-24. The company’s solid financial standing is seen as a buffer against financing risks, supported by a robust current ratio of 12.75 and minimal debt-to-equity ratio of 0.02, according to recent financial data.

The firm’s commentary indicates that the stock’s current trading price in the low-$30s and market capitalization of $3.9 billion could lead to a significant rebound if there are changes in the Health and Human Services (HHS), Food and Drug Administration (FDA), or Centers for Disease Control and Prevention (CDC) leadership, or if there is a shift to a less aggressive stance on vaccines in the future. While the stock has declined over 73% in the past six months, InvestingPro’s comprehensive analysis and Fair Value assessment suggest the stock is currently fairly valued. For deeper insights, investors can access the detailed Pro Research Report available for PCVX, along with reports for 1,400+ other US stocks.

In other recent news, Novavax (NASDAQ:NVAX) is facing challenges following comments from Health and Human Services Secretary Robert F. Kennedy Jr. regarding a shift in U.S. government priorities away from single antigen vaccines, which could impact Novavax’s Covid-19 vaccine approval process. The company is still awaiting a decision from the FDA on its vaccine approval application, with delays attributed to the type of vaccine Novavax produces. Meanwhile, Vaxcyte has been in the spotlight with several updates on its vaccine candidates. Goldman Sachs adjusted its price target for Vaxcyte to $100, citing Phase 2 results for VAX-24 in infants that did not meet certain non-inferiority criteria. Despite this, the firm maintained a Buy rating on the stock. Jefferies and Guggenheim also reiterated their Buy ratings for Vaxcyte, with price targets of $146 and $160, respectively, emphasizing positive data from the VAX-31 infant study. Vaxcyte continues to explore enhancements for its vaccine candidates and plans to advance into Phase 3 trials. The company remains focused on expanding its vaccine portfolio to address the pneumococcal disease burden.

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