Stifel maintains $780 target on argenx stock after FDA nod

Published 11/04/2025, 12:58
Stifel maintains $780 target on argenx stock after FDA nod

On Friday, Stifel analysts reaffirmed their positive stance on argenx SE (NASDAQ:ARGX), maintaining a Buy rating and a $780.00 price target for the company's stock, representing significant upside from its current trading price of $546.22. According to InvestingPro data, analysts maintain a strong buy consensus with price targets ranging from $609 to $1,127. The endorsement comes in the wake of the U.S. Food and Drug Administration's approval of argenx's Vyvgart Hytrulo pre-filled syringe for self-administration, which is a significant development for the treatment of myasthenia gravis (MG) and chronic inflammatory demyelinating polyneuropathy (CIDP).

The new Vyvgart Hytrulo pre-filled syringe allows for a quick self-administration process lasting only 20-30 seconds. A notable aspect of the approval is that the labeling does not mandate healthcare provider (HCP) monitoring for hypersensitivity, unlike the existing vial-based subcutaneous presentation that requires administration by a healthcare professional. This distinction could simplify the treatment process for patients and enhance the uptake of the drug.

Stifel analysts believe that this approval represents the best possible outcome for argenx and anticipates that it will act as a catalyst for the company's ongoing product launches in MG and CIDP markets. Management has indicated that the addition of patients in the MG category has been significantly influenced by the subcutaneous form of treatment. Analysts suggest that the pre-filled syringe could further encourage the trend of adopting this treatment earlier in the patient care process.

Looking forward, Stifel's analysts remain optimistic about the future of FcRn inhibitors and related treatment modalities. They consider argenx to be a compelling investment, particularly in the face of broader market uncertainties, citing the company's robust commercial launch activities and the potential for sustained profitability. InvestingPro data supports this outlook, revealing impressive revenue growth of 77% in the last twelve months and a strong financial health score of 3.21 out of 5, rated as "GREAT." The company maintains excellent liquidity with a current ratio of 7.29 and holds more cash than debt on its balance sheet.

Additionally, the timely approval of Vyvgart Hytrulo by the FDA is seen as a reassuring sign of the agency's operational effectiveness amidst broader concerns about regulatory challenges. The FDA's endorsement is viewed as a positive indicator for argenx and for the regulatory environment as a whole. With a market capitalization of $34.81 billion and strong profitability metrics, argenx appears undervalued according to InvestingPro Fair Value analysis. Investors seeking deeper insights can access the comprehensive Pro Research Report, available exclusively to InvestingPro subscribers, which includes detailed analysis of argenx's financial health, growth prospects, and market position.

In other recent news, Argenx SE has received significant attention following the FDA's approval of the Vyvgart prefilled syringe (PFS) for treating chronic inflammatory demyelinating polyneuropathy (CIDP) and generalized myasthenia gravis (gMG). This approval enables patients in the United States to self-administer the treatment at home, a convenience already available in Europe and Japan. Analysts from H.C. Wainwright, Guggenheim, and TD Cowen have maintained their Buy ratings on Argenx, with price targets set at $720, $1,100, and $761, respectively, highlighting the potential market advantage of Vyvgart's self-injection format.

Bernstein analysts have upgraded Argenx from Underperform to Outperform, significantly raising the price target to EUR755, driven by enhanced earnings projections and Vyvgart's commercial success. Deutsche Bank (ETR:DBKGn) also adjusted its stance, upgrading the stock from Sell to Hold with a new target of EUR575, reflecting a reevaluation of market conditions and Argenx's future prospects. TD Cowen expressed optimism about Argenx's growth trajectory, citing the strong international launch of Vyvgart and potential profitability by 2025.

The recent developments have reinforced Argenx's position in the biotech sector, with analysts noting the potential for growth through its robust pipeline, including Vyvgart's applications in other autoimmune diseases. The approval of the PFS is seen as a pivotal moment for Argenx, potentially boosting patient access and adoption rates. These updates suggest a promising outlook for Argenx as it continues to expand its market presence and product offerings.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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