Adaptimmune sells cell therapy assets to US WorldMeds for $55 million

Published 28/07/2025, 12:38
Adaptimmune sells cell therapy assets to US WorldMeds for $55 million

PHILADELPHIA/OXFORD - Adaptimmune Therapeutics plc (NASDAQ:ADAP), currently trading at $0.35 per share with a market capitalization of $92 million, has agreed to sell its cell therapy assets, including the marketed TECELRA therapy and pipeline candidates, to US WorldMeds for $55 million in cash, with potential for an additional $30 million in milestone payments. According to InvestingPro analysis, the company appears undervalued based on its Fair Value metrics.

The transaction, announced Monday and expected to close this week, includes the transfer of TECELRA, the first FDA-approved engineered TCR T-cell therapy, along with development-stage therapies lete-cel, afami-cel, and uza-cel.

Under the agreement, US WorldMeds will acquire all intellectual property rights exclusively related to these assets, while Adaptimmune will retain rights to its preclinical assets including PRAME, CD70, and its allogeneic program.

Adrian Rawcliffe, Adaptimmune’s CEO, said the decision came after "an extensive review of all strategic alternatives" due to the company’s financial situation, ensuring patients continue receiving TECELRA treatment without interruption. The decision comes as InvestingPro data shows the company burning through cash rapidly, with negative free cash flow of $110 million in the last twelve months despite generating revenue of $180 million.

US WorldMeds will offer employment to Adaptimmune’s US employees involved in the development and commercialization of these therapies to maintain continuity. The company will collaborate with Galapagos on the continued development of uza-cel.

The transaction will be financed through debt financing led by funds managed by Oaktree Capital Management, with participation from Athyrium Capital Management.

Following the sale, Adaptimmune plans to restructure to support the transition of these therapies while maximizing value from its remaining assets.

TD Cowen served as financial advisor to Adaptimmune, with Ropes & Gray providing legal counsel. Gibson, Dunn & Crutcher provided legal counsel to US WorldMeds.

This article is based on a press release statement from Adaptimmune Therapeutics.

In other recent news, Mizuho has downgraded Adaptimmune Therapeutics plc from an Outperform to a Neutral rating, citing concerns about the company’s financial sustainability. The research firm adjusted its price target for Adaptimmune, lowering it from $1.50 to $0.50. Despite these concerns, Mizuho noted the impressive initial success of Adaptimmune’s US commercial launch of Tecelra compared to other recent cell therapy product launches. Meanwhile, Context Therapeutics Inc. has announced the appointment of Dr. Karen Chagin as its new Chief Medical Officer. Dr. Chagin will replace Dr. Karen Smith, who will continue serving on the company’s Board of Directors. Dr. Chagin brings over a decade of experience, having played a key role in the approval of Tecelra at Adaptimmune Therapeutics. Her background includes senior roles at Tmunity Therapeutics and Kite Pharma. These developments reflect ongoing changes and strategic moves within both companies.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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