Alkermes shares retain Buy rating on narcolepsy drug promise

Published 10/10/2024, 15:20
Alkermes shares retain Buy rating on narcolepsy drug promise

On Thursday, Alkermes (NASDAQ:ALKS) maintained its Buy rating and a stock price target of $35.00, as confirmed by a leading financial firm. The endorsement follows a recent investor event where Key Opinion Leaders (KOLs) highlighted the significant unmet medical needs in narcolepsy and idiopathic hypersomnia (IH), diseases for which Alkermes is developing a promising therapeutic, ALKS 2680.

KOLs reportedly noted that ALKS 2680 has demonstrated efficacy levels surpassing those of the current standard of care. This has led Alkermes to expand its Phase II development of the drug to include IH, with plans to advance two additional orexin compounds into clinical trials in the upcoming year.

The firm's analyst believes that the stock is currently undervalued considering just the base business and the potential market for narcolepsy type 1 (NT1) treatment. The positive outlook on Alkermes' shares is based on the anticipated success of its developmental drugs and their ability to meet critical healthcare needs.

Alkermes is focused on addressing these gaps in treatment, and the progression of ALKS 2680 into further stages of development is a key aspect of this strategy. The company's commitment to advancing its orexin compounds into the clinic next year represents a significant step forward in its efforts to provide new solutions for patients with sleep disorders.

The reiterated Buy rating and maintained price target reflect confidence in Alkermes' strategic direction and the potential of its drug pipeline to deliver value to both patients and investors. The firm's analysis suggests that the company's current valuation does not fully reflect the opportunities that lie ahead with its narcolepsy and IH treatments.

In other recent news, Alkermes has been the focus of several analyst reports following its Q2 2024 revenue of $399 million, driven by strong sales of proprietary products Lybalvi and Aristada. Piper Sandler, Baird, JPMorgan, and Mizuho maintained their respective targets for the company, with Piper Sandler and Baird maintaining an Overweight and Outperform rating respectively.

Alkermes is also advancing with its investigational drug ALKS-2680, currently in Phase II studies for narcolepsy types 1 and 2, known as VIBRANCE-1 and VIBRANCE-2 respectively.

The company's management has outlined plans to progress two additional OX2R agonists into clinical trials by 2025. Alkermes is also exploring the potential of the orexin mechanism for other neurological and psychiatric conditions, as well as selected rare diseases. Alkermes is considering further development of ALKS-2680 for idiopathic hypersomnia (IH), based on unmet needs and positive feedback from patient groups and clinicians.

Furthermore, Alkermes' research into the orexin drug class has been highlighted as a strategic move to diversify its therapeutic offerings. Analysts from firms such as Baird, JPMorgan, and Mizuho have maintained neutral to positive ratings on Alkermes, citing the potential of ALKS-2680 as a leading treatment for narcolepsy. These are among the recent developments at Alkermes.

InvestingPro Insights

Alkermes' (NASDAQ:ALKS) strong financial position and market performance align well with the positive outlook presented in the article. According to InvestingPro data, the company boasts a market capitalization of $4.38 billion and a favorable P/E ratio of 11.19, suggesting that the stock may indeed be undervalued as the analyst report indicates.

InvestingPro Tips highlight that Alkermes holds more cash than debt on its balance sheet, which provides financial flexibility to support its ongoing research and development efforts, including the advancement of ALKS 2680 and other orexin compounds. Moreover, the company's strong return over the last three months, with a 15.56% price total return, reflects growing investor confidence in Alkermes' strategic direction and pipeline potential.

The company's profitability over the last twelve months and analysts' predictions of continued profitability this year further support the positive outlook. With a gross profit margin of 83.31% and an operating income margin of 20.1%, Alkermes demonstrates strong financial performance that could fuel its expansion into new treatment areas like narcolepsy and idiopathic hypersomnia.

For investors seeking more comprehensive analysis, InvestingPro offers additional tips and insights, with 10 tips available for Alkermes, providing a deeper understanding of the company's potential and market position.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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