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Genmab's Epcoritamab gains positive CHMP opinion

Published 28/06/2024, 20:30
GMAB
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Genmab A/S (NASDAQ:GMAB), a biotechnology company specializing in antibody therapeutics, announced today that its investigational drug Epcoritamab (TEPKINLY®) has received a positive opinion from the Committee for Medicinal Products for Human Use (CHMP). This recommendation is for the treatment of adult patients with relapsed or refractory follicular lymphoma, a type of non-Hodgkin lymphoma.

The CHMP's favorable opinion is a crucial step towards potential marketing authorization in the European Union. It is based on data demonstrating the efficacy and safety of Epcoritamab in clinical trials. The CHMP's recommendation will now be reviewed by the European Commission, which has the authority to approve the drug's use in EU member states.

Epcoritamab is part of Genmab's innovative pipeline of pharmaceutical preparations and represents a significant advancement in the treatment of hematological malignancies. The drug functions as a bispecific antibody, designed to engage both the CD3 receptor on T-cells and the CD20 antigen on B-cells, leading to the destruction of cancerous cells.

Genmab's Executive Vice President & Chief Financial Officer, Anthony Pagano, signed the SEC filing on behalf of the company, underscoring the importance of this development. The positive CHMP opinion is expected to enhance Genmab's reputation in the field of oncology and may contribute to its growth in the pharmaceutical market.

The news is based on a press release statement.

In other recent news, Genmab A/S, a Copenhagen-based pharmaceutical company, has seen significant developments. The company completed its share buyback program, a key part of its capital allocation strategy. Concurrently, Genmab's EPKINLY® received FDA approval for the treatment of relapsed or refractory follicular lymphoma, a development that led to stock upgrades by H.C. Wainwright and BTIG.

The company also reported substantial revenue growth in the first quarter of 2024, driven by robust sales of DARZALEX and KESIMPTA. In a strategic move, Genmab completed a $1.8 billion acquisition of ProfoundBio, Inc., acquiring global rights to three clinical-stage candidates and novel ADC technology platforms.

Genmab's drug Acasun, used in the treatment of PD-1 progressed lung cancer, was highlighted by Truist Securities as a potential $2 billion revenue opportunity, leading to a stock upgrade and a price target increase to $53 from $50. BTIG raised its price target for Genmab to $47.00 from the previous $46.00, maintaining a Buy rating following the FDA's accelerated approval of Epkinly.

These are the recent developments at Genmab A/S.

InvestingPro Insights

With Genmab A/S (NASDAQ:GMAB) reaching a pivotal moment in its growth trajectory, the financial metrics and expert analysis provided by InvestingPro offer valuable context for investors. As of the last twelve months as of Q1 2024, Genmab holds a market capitalization of 15.93 billion USD, reflecting its significant presence in the biotechnology sector. The company's P/E ratio stands at 20.93, indicating investor expectations for future earnings. Importantly, Genmab's gross profit margin is an impressive 97.69%, suggesting efficient operations and strong pricing power within its market niche.

InvestingPro Tips highlight that Genmab holds more cash than debt on its balance sheet, providing financial stability and flexibility. Additionally, analysts predict the company will be profitable this year, which could be a reassuring sign for investors considering the company's recent developments. For those seeking a deeper dive into Genmab's financials and performance, InvestingPro has 8 additional tips available, which can be accessed at https://www.investing.com/pro/GMAB. Use coupon code PRONEWS24 to get an additional 10% off a yearly or biyearly Pro and Pro+ subscription, adding even more value to your investment research toolkit.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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