TNF Pharmaceuticals uses AI to refine patient selection for trials

Published 22/04/2025, 14:22
TNF Pharmaceuticals uses AI to refine patient selection for trials

BALTIMORE - TNF Pharmaceuticals, Inc. (NASDAQ:TNFA), a micro-cap biotech company currently valued at $1.74 million and trading at $0.17 per share, in partnership with Renova Health, has implemented artificial intelligence (AI) and machine learning technologies to enhance patient identification for clinical studies. According to InvestingPro analysis, the company maintains a strong cash position relative to debt, though its stock has experienced significant volatility, trading near its 52-week low. This initiative aims to optimize the recruitment process for trials assessing the efficacy of isomyosamine, a drug developed for muscle mass preservation during GLP-1 treatment in conditions like diabetes and chronic weight management. With a current ratio of 1.4 and minimal debt on its balance sheet, the company appears positioned to continue its research initiatives. For deeper insights into TNFA’s financial health and growth potential, InvestingPro subscribers have access to over 13 additional key metrics and analysis tools.

The collaboration utilizes Renova Health’s AI platform, which includes natural language processing (NLP) and large language models (LLM), to analyze data from 30,000 patients. This analysis is designed to pinpoint high-risk patient groups who could potentially benefit most from isomyosamine treatment. These groups typically have underlying chronic diseases such as diabetes, COPD, chronic kidney disease, or sarcopenia/frailty, and may have experienced an acute medical event related to inflammation.

Mitchell Glass, M.D., President and Chief Medical Officer of TNF Pharmaceuticals, highlighted the technology’s ability to sift through vast patient data to identify specific subsets for their treatment. According to Glass, this approach will enable more efficient progression of the company’s study series in the upcoming months.

David Jacobs, CEO of Renova Health, expressed enthusiasm about the partnership’s potential to advance precision medicine. He emphasized the platform’s ability to create highly specific patient personas and identify optimal cohorts for isomyosamine treatment, taking into account individual physician practices and diagnosis codes.

Isomyosamine is a novel plant alkaloid small molecule that regulates the immuno-metabolic system by modulating pro-inflammatory cytokines, including TNF-alpha, which plays a role in inflammation and aging-related diseases. TNF Pharmaceuticals is also developing a second drug platform, Supera-CBD, targeting chronic pain, addiction, and epilepsy.

The press release includes forward-looking statements about the company’s research and development efforts. These statements are subject to various risks and uncertainties and reflect the company’s predictions and expectations as of the date they were made.

This news article is based on a press release statement from TNF Pharmaceuticals, Inc. and does not contain any promotional content or endorsements. The company’s next earnings report is scheduled for May 14, 2025. InvestingPro analysis indicates the stock is currently trading below its Fair Value, with comprehensive financial health metrics and detailed analysis available to subscribers.

In other recent news, TNF Pharmaceuticals is facing potential delisting from the Nasdaq Stock Market after failing to maintain a minimum bid price of $1.00 per share over a 30-day period. The company has been granted a 180-day compliance period, ending on September 15, 2025, to rectify the situation. Should TNF Pharmaceuticals fail to meet the requirement, it may be eligible for an additional 180-day period if it meets other initial listing standards. Meanwhile, TNF Pharmaceuticals recently held a conference call to discuss advancements in their lead compound, Isomyosamine. The details of the call have been made available in a transcript attached to a Form 8-K filed with the SEC. The company has emphasized that the information shared during the call is not considered "filed" for purposes of certain regulatory liabilities. TNF Pharmaceuticals continues to prioritize transparency and regular communication with its stakeholders regarding its research and development efforts.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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