Roche shares down over 2% after Q3 sales miss; outlook raised but in-line

Published 23/10/2025, 06:18
Updated 23/10/2025, 11:52
© Reuters.

Investing.com -- Roche Holding AG (SIX:RO) shares fell more than 2% on Thursday after the Swiss pharmaceutical group reported third-quarter sales that missed analyst expectations by 2%, with several key growth drugs underperforming and a raised full-year outlook already matching consensus forecasts.

Group sales reached CHF14.92 billion, compared with the CHF15.17 billion expected. Pharmaceutical sales were CHF11.57 billion, about 2% below forecasts, while Diagnostics came broadly in line at CHF3.35 billion. 

“3Q Sales -2% v cons, with Pharma -2%, Diagnostics in-line,” Jefferies said in a note. Roche’s shares last closed at CHF280.50, with Jefferies maintaining a “hold” rating and a price target of CHF270.

Among Roche’s major drugs, Hemlibra sales were 5% below consensus, Ocrevus missed by 3%, and Vabysmo was 11% under expectations. 

Jefferies noted that “focus drugs Phesgo, slightly ahead, Hemlibra miss (-5%), Vabysmo miss (-11%), Ocrevus miss (-3%). Legacy products offset but hence not great quality.” 

Older treatments such as Rituxan and Actemra outperformed, up 12% and 4% against estimates, respectively, partially offsetting the shortfall from newer medicines.

Roche lifted its full-year sales guidance to a range of CHF61 billion to CHF63 billion at constant exchange rates, compared with Visible Alpha’s consensus of CHF61.8 billion. 

“Outlook raised but consensus there, EPS guide may disappoint,” Jefferies said. The brokerage estimated mid–single-digit growth at constant exchange rates, implying group sales between CHF61.21 billion and CHF62.93 billion, based on Roche’s own currency impact assumptions.

The company forecast diluted core earnings per share to grow in the high-single- to low-double-digit range at constant exchange rates, up from its prior guidance of high-single-digit growth. 

Jefferies calculated an EPS range of CHF19.21 to CHF19.92, assuming an 8% foreign exchange impact, against consensus expectations of CHF19.89. 

“Earnings outlook is high-single-digit to low double-digit CER (from high-single-digit), leaving cons CHF19.89 when using the company’s FX guide of -8% impact right at the top of the guidance range,” the brokerage said.

Latest comments

Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers
© 2007-2025 - Fusion Media Limited. All Rights Reserved.